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Alkylated epidermal creatine kinase as a biomarker for sulfur mustard exposure: comparison to adducts of albumin and DNA in an in vivo rat study

2021 . Steinritz, Dirk | Lüling, Robin | Siegert, Markus | Herbert, Julia | Mückter, Harald | Taeger, Christian D. | Gudermann, Thomas | Dietrich, Alexander | Thiermann, Horst | John, Harald

Toxicokinetics of U-47700, tramadol, and their main metabolites in pigs following intravenous administration: is a multiple species allometric scaling approach useful for the extrapolation of toxicokinetic parameters to humans?

2021 . Nordmeier, Frederike | Sihinevich, Iryna | Doerr, Adrian A. | Walle, Nadja | Laschke, Matthias W. | Lehr, Thorsten | Menger, Michael D. | Schmidt, Peter H. | Meyer, Markus R. | Schaefer, Nadine

Post-VX exposure treatment of rats with engineered phosphotriesterases

2021 . Stigler, Lisa | Köhler, Anja | Koller, Marianne | Job, Laura | Escher, Benjamin | Potschka, Heidrun | Thiermann, Horst | Skerra, Arne | Worek, Franz | Wille, Timo

Sex-dependent dynamics of metabolism in primary mouse hepatocytes

2021 . Hochmuth, Luise | Körner, Christiane | Ott, Fritzi | Volke, Daniela | Blagotinšek Cokan, Kaja | Juvan, Peter | Brosch, Mario | Hofmann, Ute | Hoffmann, Ralf | Rozman, Damjana | Berg, Thomas | Matz-Soja, Madlen

Altered metabolic pathways elucidated via untargeted in vivo toxicometabolomics in rat urine and plasma samples collected after controlled application of a human equivalent amphetamine dose

2021 . Hemmer, Selina | Wagmann, Lea | Meyer, Markus R.

Role of hepcidin in oxidative stress and cell death of cultured mouse renal collecting duct cells: protection against iron and sensitization to cadmium

2021 . Probst, Stephanie | Fels, Johannes | Scharner, Bettina | Wolff, Natascha A. | Roussa, Eleni | van Swelm, Rachel | Lee, Wing-Kee | Thévenod, Frank

Is adipose tissue suitable for detection of (synthetic) cannabinoids? A comparative study analyzing antemortem and postmortem specimens following pulmonary administration of JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol to pigs

2020 . Schaefer, Nadine | Nordmeier, Frederike | Kröll, Ann-Katrin | Körbel, Christina | Laschke, Matthias W. | Menger, Michael D. | Maurer, Hans H. | Meyer, Markus R. | Schmidt, Peter H.

Structure-dependent genotoxic potencies of selected pyrrolizidine alkaloids in metabolically competent HepG2 cells

2020 . Rutz, Lukas | Gao, Lan | Küpper, Jan-Heiner | Schrenk, Dieter

In vitro biotransformation of pyrrolizidine alkaloids in different species: part II—identification and quantitative assessment of the metabolite profile of six structurally different pyrrolizidine alkaloids

2020 . Geburek, Ina | Schrenk, Dieter | These, Anja