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Alkylated epidermal creatine kinase as a biomarker for sulfur mustard exposure: comparison to adducts of albumin and DNA in an in vivo rat study

2021 . Steinritz, Dirk | Lüling, Robin | Siegert, Markus | Herbert, Julia | Mückter, Harald | Taeger, Christian D. | Gudermann, Thomas | Dietrich, Alexander | Thiermann, Horst | John, Harald

Toxicokinetics of U-47700, tramadol, and their main metabolites in pigs following intravenous administration: is a multiple species allometric scaling approach useful for the extrapolation of toxicokinetic parameters to humans?

2021 . Nordmeier, Frederike | Sihinevich, Iryna | Doerr, Adrian A. | Walle, Nadja | Laschke, Matthias W. | Lehr, Thorsten | Menger, Michael D. | Schmidt, Peter H. | Meyer, Markus R. | Schaefer, Nadine

Sex-dependent dynamics of metabolism in primary mouse hepatocytes

2021 . Hochmuth, Luise | Körner, Christiane | Ott, Fritzi | Volke, Daniela | Blagotinšek Cokan, Kaja | Juvan, Peter | Brosch, Mario | Hofmann, Ute | Hoffmann, Ralf | Rozman, Damjana | Berg, Thomas | Matz-Soja, Madlen

Altered metabolic pathways elucidated via untargeted in vivo toxicometabolomics in rat urine and plasma samples collected after controlled application of a human equivalent amphetamine dose

2021 . Hemmer, Selina | Wagmann, Lea | Meyer, Markus R.

Cross-species analysis of hepatic cytochrome P450 and transport protein expression

2020 . Hammer, Helen | Schmidt, Felix | Marx-Stoelting, Philip | Pötz, Oliver | Braeuning, Albert

Is adipose tissue suitable for detection of (synthetic) cannabinoids? A comparative study analyzing antemortem and postmortem specimens following pulmonary administration of JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol to pigs

2020 . Schaefer, Nadine | Nordmeier, Frederike | Kröll, Ann-Katrin | Körbel, Christina | Laschke, Matthias W. | Menger, Michael D. | Maurer, Hans H. | Meyer, Markus R. | Schmidt, Peter H.

In vitro biotransformation of pyrrolizidine alkaloids in different species: part II—identification and quantitative assessment of the metabolite profile of six structurally different pyrrolizidine alkaloids

2020 . Geburek, Ina | Schrenk, Dieter | These, Anja