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Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers

2024 . Jessen, Marco | Gertzmann, Dörthe | Liss, Franziska | Zenk, Franziska | Bähner, Laura | Schöffler, Victoria | Schulte, Clemens | Maric, Hans Michael | Ade, Carsten | von Eyss, Bjoern | Gaubatz, Stefan

The androgen receptor—lncRNASAT1-AKT-p15 axis mediates androgen-induced cellular senescence in prostate cancer cells

2021 . Mirzakhani, Kimia | Kallenbach, Julia | Rasa, Seyed Mohammad Mahdi | Ribaudo, Federico | Ungelenk, Martin | Ehsani, Marzieh | Gong, Wenrong | Gassler, Nikolaus | Leeder, Mirjam | Grimm, Marc-Oliver | Neri, Francesco | Baniahmad, Aria

Stromal NRG1 in luminal breast cancer defines pro-fibrotic and migratory cancer-associated fibroblasts

CHD5 inhibits metastasis of neuroblastoma

2021 . Laut, Astrid K. | Dorneburg, Carmen | Fürstberger, Axel | Barth, Thomas F. E. | Kestler, Hans A. | Debatin, Klaus-Michael | Beltinger, Christian

Applicability of liquid biopsies to represent the mutational profile of tumor tissue from different cancer entities

2021 . Liebs, Sandra | Eder, Theresa | Klauschen, Frederick | Schütte, Moritz | Yaspo, Marie-Laure | Keilholz, Ulrich | Tinhofer, Ingeborg | Kidess-Sigal, Evelyn | Braunholz, Diana

Oct4 confers stemness and radioresistance to head and neck squamous cell carcinoma by regulating the homologous recombination factors PSMC3IP and RAD54L

2021 . Nathansen, Jacqueline | Lukiyanchuk, Vasyl | Hein, Linda | Stolte, Maya-Isabel | Borgmann, Kerstin | Löck, Steffen | Kurth, Ina | Baumann, Michael | Krause, Mechthild | Linge, Annett | Dubrovska, Anna

The age of adult pilocytic astrocytoma cells

2021 . Voronina, Natalia | Aichmüller, Christian | Kolb, Thorsten | Korshunov, Andrey | Ryzhova, Marina | Barnholtz-Sloan, Jill | Cioffi, Gino | Sill, Martin | von Deimling, Andreas | Pfister, Stefan M. | Gronych, Jan | Jones, David T. W. | Frisén, Jonas | Zapatka, Marc | Ernst, Aurelie

DNA-methylation patterns imply a common cellular origin of virus- and UV-associated Merkel cell carcinoma

2021 . Gravemeyer, Jan | Spassova, Ivelina | Verhaegen, Monique | Dlugosz, Andrzej | Hoffmann, Daniel | , Anja | Becker, Jürgen

The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis

2021 . Kobelt, Dennis | Perez Hernandez, Daniel | Fleuter, Claudia | Dahlmann, Mathias | Zincke, Fabian | Smith, Janice | Migotti, Rebekka | Popp, Oliver | Burock, Susen | Walther, Wolfgang | Dittmar, Gunnar | Mertins, Philipp | Stein, Ulrike

Porcine model elucidates function of p53 isoform in carcinogenesis and reveals novel circTP53 RNA

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