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Oct4 confers stemness and radioresistance to head and neck squamous cell carcinoma by regulating the homologous recombination factors PSMC3IP and RAD54L

2021 . Nathansen, Jacqueline | Lukiyanchuk, Vasyl | Hein, Linda | Stolte, Maya-Isabel | Borgmann, Kerstin | Löck, Steffen | Kurth, Ina | Baumann, Michael | Krause, Mechthild | Linge, Annett | Dubrovska, Anna

CHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo

In cis TP53 and RAD51C pathogenic variants may predispose to sebaceous gland carcinomas

2020 . Le Duc, Diana | Hentschel, Julia | Neuser, Sonja | Stiller, Mathias | Meier, Carolin | Jäger, Elisabeth | Abou Jamra, Rami | Platzer, Konrad | Monecke, Astrid | Ziemer, Mirjana | Markovic, Aleksander | Bläker, Hendrik | Lemke, Johannes

Distinct genomic subclasses of high-grade/progressive meningiomas: NF2-associated, NF2-exclusive, and NF2-agnostic

2020 . Williams, Erik A. | Santagata, Sandro | Wakimoto, Hiroaki | Shankar, Ganesh M. | Barker, Fred G. | Sharaf, Radwa | Reddy, Abhinav | Spear, Phoebe | Alexander, Brian M. | Ross, Jeffrey S. | Brastianos, Priscilla K. | Cahill, Daniel P. | Ramkissoon, Shakti H. | Juratli, Tareq

PRDM8 reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation

2020 . Cypris, Olivia | Eipel, Monika | Franzen, Julia | Rösseler, Corinna | Tharmapalan, Vithurithra | Kuo, Chao-Chung | Vieri, Margherita | Nikolić, Miloš | Kirschner, Martin | Brümmendorf, Tim H. | Zenke, Martin | Lampert, Angelika | Beier, Fabian | Wagner, Wolfgang

Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1