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KRAS and TP53 co-mutation predicts benefit of immune checkpoint blockade in lung adenocarcinoma

Continued decitabine/all-trans retinoic acid treatment: extended complete remission in an elderly AML patient with multi-hit TP53 lesions and complex-monosomal karyotype

2024 . Thomas, Johanna | Rehman, Usama-Ur | Bresser, Helena | Grishina, Olga | Pfeifer, Dietmar | Sollier, Etienne | Döhner, Konstanze | Plass, Christoph | Becker, Heiko | Schmoor, Claudia | de Wit, Maike | Lübbert, Michael

Cell-autonomous IL6ST activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment

Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1

p53 is functionally inhibited in clear cell renal cell carcinoma (ccRCC): a mechanistic and correlative investigation into genetic and molecular characteristics

2021 . Diesing, Karoline | Ribback, Silvia | Winter, Stefan | Gellert, Manuela | Oster, Antonia M. | Stühler, Viktoria | Gläser, Eva | Adler, Frank | Hartwig, Christoph | Scharpf, Markus | Bedke, Jens | Burchardt, Martin | Schwab, Matthias | Lillig, Christopher H. | Kroeger, Nils

Case Report: Identification of Potential Prognosis-Related TP53 Mutation and BCL6-LPP Fusion in Primary Pituitary Lymphoma by Next Generation Sequencing: Two Cases

2021 . Zhang, Yi | Ma, Liyuan | Liu, Jie | Zhu, Huijuan | Lu, Lin | Deng, Kan | Ma, Wenbin | Pan, Hui | Wang, Renzhi | Yao, Yong

Lymphocyte activation gene 3 (LAG3) protein expression on tumor-infiltrating lymphocytes in aggressive and TP53-mutated salivary gland carcinomas

2020 . Arolt, Christoph | Meyer, Moritz | Ruesseler, Vanessa | Nachtsheim, Lisa | Wuerdemann, Nora | Dreyer, Thomas | Gattenlöhner, Stefan | Wittekindt, Claus | Buettner, Reinhard | Quaas, Alexander | Klussmann, Jens Peter

Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia

In cis TP53 and RAD51C pathogenic variants may predispose to sebaceous gland carcinomas

2020 . Le Duc, Diana | Hentschel, Julia | Neuser, Sonja | Stiller, Mathias | Meier, Carolin | Jäger, Elisabeth | Abou Jamra, Rami | Platzer, Konrad | Monecke, Astrid | Ziemer, Mirjana | Markovic, Aleksander | Bläker, Hendrik | Lemke, Johannes

TP53 germline mutations in the context of families with hereditary breast and ovarian cancer: a clinical challenge

2020 . Grill, Sabine | Ramser, Juliane | Hellebrand, Heide | Pfarr, Nicole | Boxberg, Melanie | Brambs, Christine | Ditsch, Nina | Meindl, Alfons | Groß, Eva | Meitinger, Thomas | Kiechle, Marion | Quante, Anne S.

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