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p53 and MYC-regulated squalene epoxidase as Achilles heel in colorectal cancer

2023 . Fischer, Martin

The majority of β-catenin mutations in colorectal cancer is homozygous

2020 . Arnold, Alexander | Tronser, Moritz | Sers, Christine | Ahadova, Aysel | Endris, Volker | Mamlouk, Soulafa | Horst, David | Möbs, Markus | Bischoff, Philip | Kloor, Matthias | Bläker, Hendrik

Current treatment options in RAS mutant metastatic colorectal cancer patients: a meta-analysis of 14 randomized phase III trials

2020 . Stahler, Arndt | Heinemann, Volker | Ricard, Ingrid | von Einem, Jobst C. | Giessen-Jung, Clemens | Westphalen, Christoph Benedikt | Michl, Marlies | Heinrich, Kathrin | Miller-Phillips, Lisa | Jelas, Ivan | Stintzing, Sebastian | Modest, Dominik Paul

Biomarker alterations associated with distinct patterns of metastatic spread in colorectal cancer

2020 . Michl, M. | Taverna, F. | Kumbrink, J. | Schiergens, T. S. | Heinemann, V. | Engel, J. | Kirchner, T. | Neumann, Jens

Dynamics in treatment response and disease progression of metastatic colorectal cancer (mCRC) patients with focus on BRAF status and primary tumor location: analysis of untreated RAS-wild-type mCRC patients receiving FOLFOXIRI either with or without panitumumab in the VOLFI trial (AIO KRK0109)

BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation

2020 . Reischmann, Nadine | Andrieux, Geoffroy | Griffin, Ricarda | Reinheckel, Thomas | Boerries, Melanie | Brummer, Tilman