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Selective degradation of mutant FMS-like tyrosine kinase-3 requires BIM-dependent depletion of heat shock proteins

2024 . Halilovic, Melisa | Abdelsalam, Mohamed | Zabkiewicz, Joanna | Lazenby, Michelle | Alvares, Caroline | Schmidt, Matthias | Brenner, Walburgis | Najafi, Sara | Oehme, Ina | Hieber, Christoph | Zeyn, Yanira | Bros, Matthias | Sippl, Wolfgang | Krämer, Oliver

Context-specific effects of NOX4 inactivation in acute myeloid leukemia (AML)

2022 . Demircan, Muhammed Burak | Schnoeder, Tina M. | Mgbecheta, Peter C. | Schröder, Katrin | Böhmer, Frank-D. | Heidel, Florian

Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies

2021 . Decker, Melanie | Lammens, Tim | Ferster, Alina | Erlacher, Miriam | Yoshimi, Ayami | Niemeyer, Charlotte | Ernst, Martijn P. T. | Raaijmakers, Marc H. G. P. | Duployez, Nicolas | Flaum, Andreas | Steinemann, Doris | Schlegelberger, Brigitte | Illig, Thomas | Ripperger, Tim

YBX1 mediates translation of oncogenic transcripts to control cell competition in AML

The IL-3, IL-5, and GM-CSF common receptor beta chain mediates oncogenic activity of FLT3-ITD-positive AML

Investigation of measurable residual disease in acute myeloid leukemia by DNA methylation patterns

2021 . Božić, Tanja | Kuo, Chao-Chung | Hapala, Jan | Franzen, Julia | Eipel, Monika | Platzbecker, Uwe | Kirschner, Martin | Beier, Fabian | Jost, Edgar | Thiede, Christian | Wagner, Wolfgang

Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo

2021 . Spohr, Corinna | Poggio, Teresa | ANDRIEUX, GEOFFROY | Schönberger, Katharina | Cabezas-Wallscheid, Nina | Boerries, Melanie | Halbach, Sebastian | Illert, Anna L. | Brummer, Tilman

Deep learning detects acute myeloid leukemia and predicts NPM1 mutation status from bone marrow smears

2021 . Eckardt, Jan-Niklas | Middeke, Jan Moritz | Riechert, Sebastian | Schmittmann, Tim | Sulaiman, Anas Shekh | Kramer, Michael | Sockel, Katja | Kroschinsky, Frank | Schuler, Ulrich | Schetelig, Johannes | Röllig, Christoph | Thiede, Christian | Wendt, Karsten | Bornhauser, Martin

Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia