Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial

2022 . Hagel, Stefan | Bach, Friedhelm | Brenner, Thorsten | Bracht, Hendrik | Brinkmann, Alexander | Annecke, Thorsten | Hohn, Andreas | Weigand, Markus | Michels, Guido | Kluge, Stefan | Nierhaus, Axel | Jarczak, Dominik | König, Christina | Weismann, Dirk | Frey, Otto | Witzke, Dominic | Müller, Carsten | Bauer, Michael | Kiehntopf, Michael | Neugebauer, Sophie | Lehmann, Thomas | Roberts, Jason A. | Pletz, Mathias W. | the TARGET Trial Investigators | Braune, Anke | Schmidt, Karsten | Motsch, Johann | Pinder, Nadine | Richter, Daniel | Schlattmann, Peter | Ameln-Mayerhofer von, Andreas | Schappacher, Markus | Fuchs, Thomas | Röhr, Anka | Kurlbaum, Max | Schreiner, Oliver | Hüter, Lars | Gründling, Matthias | Angermair, Stefan | Deja, Maria | Bloos, Frank | Fiedler, Sandra | Chkirni, Hicham