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Combined vaccine-immune-checkpoint inhibition constitutes a promising strategy for treatment of dMMR tumors

2021 . Salewski, Inken | Kuntoff, Steffen | Kuemmel, Andreas | Feldtmann, Rico | Felix, Stephan B. | Henze, Larissa | Junghanss, Christian | , Claudia

Deep abscopal response to radiotherapy and anti-PD-1 in an oligometastatic melanoma patient with unfavorable pretreatment immune signature

2020 . Watanabe, Tsubasa | Firat, Elke | Scholber, Jutta | Gaedicke, Simone | Heinrich, Corinne | Luo, Ren | Ehrat, Nicolas | Multhoff, Gabriele | Schmitt-Graeff, Annette | Grosu, Anca-Ligia | Abdollahi, Amir | Hassel, Jessica C. | von Bubnoff, Dagmar | Meiss, Frank | Niedermann, Gabriele

Induction of cytotoxic effector cells towards cholangiocellular, pancreatic, and colorectal tumor cells by activation of the immune checkpoint CD40/CD40L on dendritic cells

2020 . Sadeghlar, Farsaneh | Vogt, Annabelle | Mohr, Raphael U. | Mahn, Robert | van Beekum, Katrin | Kornek, Miroslaw | Weismüller, Tobias J. | Branchi, Vittorio | Matthaei, Hanno | Toma, Marieta | Schmidt-Wolf, I. G. H. | Kalff, Jörg C. | Strassburg, Christian P. | González-Carmona, Maria A.

Talimogene laherparepvec treatment to overcome loco-regional acquired resistance to immune checkpoint blockade in tumor stage IIIB–IV M1c melanoma patients

2020 . Fröhlich, Anne | Niebel, Dennis | Fietz, Simon | Egger, Eva | Buchner, Andrea | Sirokay, Judith | Landsberg, Jennifer

Anti-PD-1 antibody increases NK cell cytotoxicity towards nasopharyngeal carcinoma cells in the context of chemotherapy-induced upregulation of PD-1 and PD-L1

2020 . Makowska, Anna | Meier, Selina | Shen, Lian | Busson, Pierre | Baloche, Valentin | Kontny, Udo