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Alkylated epidermal creatine kinase as a biomarker for sulfur mustard exposure: comparison to adducts of albumin and DNA in an in vivo rat study

2021 . Steinritz, Dirk | Lüling, Robin | Siegert, Markus | Herbert, Julia | Mückter, Harald | Taeger, Christian D. | Gudermann, Thomas | Dietrich, Alexander | Thiermann, Horst | John, Harald

Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative defense

2021 . Tigges, Jonas | Worek, Franz | Thiermann, Horst | Wille, Timo

Transcriptomics analysis of hepatotoxicity induced by the pesticides imazalil, thiacloprid and clothianidin alone or in binary mixtures in a 28-day study in female Wistar rats

2021 . Alarcan, Jimmy | Sprenger, Heike | Waizenegger, Julia | Lichtenstein, Dajana | Luckert, Claudia | Marx-Stoelting, Philip | Lampen, Alfonso | Braeuning, Albert

Post-VX exposure treatment of rats with engineered phosphotriesterases

2021 . Stigler, Lisa | Köhler, Anja | Koller, Marianne | Job, Laura | Escher, Benjamin | Potschka, Heidrun | Thiermann, Horst | Skerra, Arne | Worek, Franz | Wille, Timo

Prediction of the dose range for adverse neurological effects of amiodarone in patients from an in vitro toxicity test by in vitro–in vivo extrapolation

2021 . Algharably, Engi | Di Consiglio, Emma | Testai, Emanuela | Kreutz, Reinhold | Gundert-Remy, Ursula

Altered metabolic pathways elucidated via untargeted in vivo toxicometabolomics in rat urine and plasma samples collected after controlled application of a human equivalent amphetamine dose

2021 . Hemmer, Selina | Wagmann, Lea | Meyer, Markus R.

Hepatotoxicity of pyrrolizidine alkaloids in rats in relation to human exposure

2020 . Bolt, Hermann M.

Following the adverse outcome pathway from micronucleus to cancer using H2B-eGFP transgenic healthy stem cells

2020 . Hölzel, Bastian Niklas | Pfannkuche, Kurt Paul | Allner, Bernhard | Allner, Hans Thomas | Hescheler, Jürgen | Derichsweiler, Daniel | Hollert, Henner | Schiwy, Andreas | Brendt, Julia | Schaffeld, Michael | Froschauer, Alexander | Stahlschmidt-Allner, Petra

Super-resolution microscopy unveils transmembrane domain-mediated internalization of cross-reacting material 197 into diphtheria toxin-resistant mouse J774A.1 cells and primary rat fibroblasts in vitro

2020 . Fellermann, Maximilian | Wondany, Fanny | Carle, Stefan | Nemeth, Julia | Sadhanasatish, Tanmay | Frick, Manfred | Barth, Holger | Michaelis, Jens

In vitro biotransformation of pyrrolizidine alkaloids in different species: part II—identification and quantitative assessment of the metabolite profile of six structurally different pyrrolizidine alkaloids

2020 . Geburek, Ina | Schrenk, Dieter | These, Anja