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Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: implications for Alzheimer disease pathogenesis

2024 . Terron, Heather M. | Parikh, Sagar J. | Abdul-Hay, Samer O. | Sahara, Tomoko | Kang, Dongcheul | Dickson, Dennis W. | Saftig, Paul | LaFerla, Frank M. | Lane, Shelley | Leissring, Malcolm A.

pTau pathology in the retina of TAU58 mice: association with ganglion cell degeneration and implications on seeding and propagation of pTau from human brain lysates

2024 . Walkiewicz, Grzegorz | Ronisz, Alicja | Ospitalieri, Simona | Tsaka, Grigoria | Tomé, Sandra O. | Vandenberghe, Rik | von Arnim, Christine A. F. | Rousseau, Frederic | Schymkowitz, Joost | De Groef, Lies | Thal, Dietmar Rudolf

Western diet increases brain metabolism and adaptive immune responses in a mouse model of amyloidosis

DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer’s disease

TREM2 modulates differential deposition of modified and non-modified Aβ species in extracellular plaques and intraneuronal deposits

2021 . JOSHI, PRANAV | Riffel, Florian | Kumar, Sathish | Villacampa, Dr Nàdia | Theil, Sandra | Parhizkar, Samira | Haass, Christian | Colonna, Marco | Heneka, Michael T. | Arzberger, Thomas | Herms, Jochen | Walter, Jochen