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Impact of therapeutic inhibition of oncogenic cell signaling tyrosine kinase on cell metabolism: in vivo-detectable metabolic biomarkers of inhibition

2024 . Nath, Kavindra | Gupta, Pradeep K. | Basappa, Johnvesly | Wang, Shengchun | Sen, Neil | Lobello, Cosimo | Tomar, Jyoti S. | Shestov, Alexander A. | Orlovskiy, Stepan | Arias-Mendoza, Fernando | Rauert-Wunderlich, Hilka | Nelson, David S. | Glickson, Jerry D. | Wasik, Mariusz A.

Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines

Pharmacokinetic–pharmacodynamic guided optimisation of dose and schedule of CGM097, an HDM2 inhibitor, in preclinical and clinical studies

Raloxifene inhibits pancreatic adenocarcinoma growth by interfering with ERβ and IL-6/gp130/STAT3 signaling

2020 . Pozios, Ioannis | Seel, Nina N. | Hering, Nina A. | Hartmann, Lisa | Liu, Verena | Camaj, Peter | Müller, Mario H. | Lee, Lucas D. | Bruns, Christiane J. | Kreis, Martin E. | Seeliger, Hendrik