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In vivo CRISPR/Cas9-mediated screen reveals a critical function of TFDP1 and E2F4 transcription factors in hematopoiesis

2024 . Tran, Ngoc-Tung | Graf, Robin | Acevedo-Ochoa, Ernesto | Trombke, Janine | Weber, Timm | Sommermann, Thomas | Salomon, Claudia | Kühn, Ralf | Rajewsky, Klaus | Chu, Van Trung

miR-147b mediated suppression of DUSP8 promotes lung cancer progression

2024 . Turkowski, Kati | Herzberg, Frederik | Günther, Stefan | Weigert, Andreas | Haselbauer, Tamara | Fink, Ludger | Brunn, David | Grimminger, Friedrich | Seeger, Werner | Sültmann, Holger | Stiewe, Thorsten | Pullamsetti, Soni Savai | Savai, Rajkumar

Selective degradation of mutant FMS-like tyrosine kinase-3 requires BIM-dependent depletion of heat shock proteins

2024 . Halilovic, Melisa | Abdelsalam, Mohamed | Zabkiewicz, Joanna | Lazenby, Michelle | Alvares, Caroline | Schmidt, Matthias | Brenner, Walburgis | Najafi, Sara | Oehme, Ina | Hieber, Christoph | Zeyn, Yanira | Bros, Matthias | Sippl, Wolfgang | Krämer, Oliver

Normalization of Snai1-mediated vessel dysfunction increases drug response in cancer