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The EU Response to the Presence of Nitrosamine Impurities in Medicines

2021 . Ruepp, Robin | Frötschl, Roland | Bream, Robert | Filancia, Maria | Girard, Thomas | Spinei, Andrei | Weise, Martina | Whomsley, Rhys

Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose

Inhibition of the PI3K but not the MEK/ERK pathway sensitizes human glioma cells to alkylating drugs

2018 . Haas, Bodo | Klinger, Veronika | Keksel, Christina | Bonigut, Verena | Kiefer, Daniela | Caspers, Julia | Walther, Julia | Wos-Maganga, Maria | Weickhardt, Sandra | Röhn, Gabriele | Timmer, Marco | Frötschl, Roland | Eckstein, Niels

Cisplatin resistance in non-small cell lung cancer cells is associated with an abrogation of cisplatin-induced G2/M cell cycle arrest

2017 . Sarin, Navin | Engel, Florian | Kalayda, Ganna V. | Mannewitz, Mareike | Cinatl Jr., Jindrich | Rothweiler, Florian | Michaelis, Martin | Saafan, Hisam | Ritter, Christoph A. | Jaehde, Ulrich | Frötschl, Roland

Identifizierung von Biomarkern zur Vorhersage genotoxischer Wirkmechanismen

2010 . Krämer, Eva | Frötschl, Roland