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Sacherschließung
radioiodide uptake
(1)
low-molecular-weight ligands
(1)
glycoprotein hormone receptors
(1)
constitutively activating mutations
(1)
allosteric small molecules
(1)
activation mechanisms
(1)
Thyrotropin receptor
(1)
TSH receptor
(1)
Silencing mutations
(1)
Signal transduction
(1)
Publikationstyp
Artikel
(5)
Erscheinungsjahr
2010
(2)
2009
(1)
2008
(1)
2006
(1)
Institution
Leibniz-Institut für Molekulare Pharmakologie
(4)
Leibniz-Forschungsinstitut für Molekulare Pharmakologie
(1)
5 Treffer
Kurzansicht
E-Jahr
Zugriff
Typ
Operations
Mutations that silence constitutive signaling activity in the allosteric ligand-binding site of the thyrotropin receptor
2010 .
Haas, Ann-Karin
|
Kleinau, Gunnar
|
Hoyer, Inna
|
Neumann, Susanne
|
Furkert, Jens
|
Rutz, Claudia
|
Schülein, Ralf
|
Gershengorn, Marvin C.
|
Krause, Gerd
2010
http://purl.org/ontology/bibo/Article
Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor
2010 .
Kleinau, Gunnar
|
Haas, Ann-Karin
|
Neumann, Susanne
|
Worth, Catherine L.
|
Hoyer, Inna
|
Furkert, Jens
|
Rutz, Claudia
|
Gershengorn, Marvin C.
|
Schülein, Ralf
|
Krause, Gerd
2010
http://purl.org/ontology/bibo/Article
Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice
2009 .
Neumann, Susanne
|
Huang, Wenwei
|
Titus, Steve
|
Krause, Gerd
|
Kleinau, Gunnar
|
Alberobello, Anna Teresa
|
Zheng, Wei
|
Southall, Noel T.
|
Inglese, James
|
Austin, Christopher P.
|
Celi, Francesco S.
|
Gavrilova, Oksana
|
Thomas, Craig J.
|
Raaka, Bruce M.
|
Gershengorn, Marvin C.
2009
http://purl.org/ontology/bibo/Article
A Low-Molecular-Weight Antagonist for the Human Thyrotropin Receptor with Therapeutic Potential for Hyperthyroidism
2008 .
Neumann, Susanne
|
Kleinau, Gunnar
|
Costanzi, Stefano
|
Moore, Susanna
|
Jiang, Jian-kang
|
Raaka, Bruce M.
|
Thomas, Craig J.
|
Krause, Gerd
|
Gershengorn, Marvin C.
2008
http://purl.org/ontology/bibo/Article
Evaluation of Small-Molecule Modulators of the Luteinizing Hormone/Choriogonadotropin and Thyroid Stimulating Hormone Receptors: Structure−Activity Relationships and Selective Binding Patterns
2006 .
Moore, Susanna
|
Jaeschke, Holger
|
Kleinau, Gunnar
|
Neumann, Susanne
|
Costanzi, Stefano
|
Jiang, Jian-kang
|
Childress, John
|
Raaka, Bruce M.
|
Colson, Anny
|
Paschke, Ralf
|
Krause, Gerd
|
Thomas, Craig J.
|
Gershengorn, Marvin C.
2006
http://purl.org/ontology/bibo/Article