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Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative defense

2021 . Tigges, Jonas | Worek, Franz | Thiermann, Horst | Wille, Timo

Transcriptomics analysis of hepatotoxicity induced by the pesticides imazalil, thiacloprid and clothianidin alone or in binary mixtures in a 28-day study in female Wistar rats

2021 . Alarcan, Jimmy | Sprenger, Heike | Waizenegger, Julia | Lichtenstein, Dajana | Luckert, Claudia | Marx-Stoelting, Philip | Lampen, Alfonso | Braeuning, Albert

Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validation

2021 . Kadioglu, Onat | Klauck, Sabine M. | Fleischer, Edmond | Shan, Letian | Efferth, Thomas

Catalytic activity and stereoselectivity of engineered phosphotriesterases towards structurally different nerve agents in vitro

2021 . Köhler, Anja | Escher, Benjamin | Job, Laura | Koller, Marianne | Thiermann, Horst | Skerra, Arne | Worek, Franz

Prediction of the dose range for adverse neurological effects of amiodarone in patients from an in vitro toxicity test by in vitro–in vivo extrapolation

2021 . Algharably, Engi | Di Consiglio, Emma | Testai, Emanuela | Kreutz, Reinhold | Gundert-Remy, Ursula

Internal exposure to perfluoroalkyl substances (PFASs) and biological markers in 101 healthy 1-year-old children: associations between levels of perfluorooctanoic acid (PFOA) and vaccine response

2020 . Abraham, Klaus | Mielke, Hans | Fromme, Hermann | Völkel, Wolfgang | Menzel, Juliane | Peiser, Matthias | Zepp, Fred | Willich, Stefan N. | Weikert, Cornelia

E-vapor aerosols do not compromise bone integrity relative to cigarette smoke after 6-month inhalation in an ApoE–/– mouse model

Autophagy alleviates amiodarone-induced hepatotoxicity

2020 . Wandrer, Franziska | Frangež, Živa | Liebig, Stephanie | John, Katharina | Vondran, Florian | Wedemeyer, Heiner | Veltmann, Christian | Pfeffer, Tobias J. | Shibolet, Oren | Schulze-Osthoff, Klaus | Simon, Hans-Uwe | Schulze-Osthoff, Klaus

Neurotoxic effects in zebrafish embryos by valproic acid and nine of its analogues: the fish-mouse connection?

2020 . Brotzmann, Katharina | Wolterbeek, André | Kroese, Dinant | Braunbeck, Thomas

Impairment of bile acid metabolism by perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) in human HepaRG hepatoma cells

2020 . Behr, Anne-Cathrin | Kwiatkowski, Anna | Ståhlman, Marcus | Schmidt, Felix Florian | Luckert, Claudia | Braeuning, Albert | Buhrke, Thorsten

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