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Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans

Remodeling of the Cardiac Extracellular Matrix Proteome During Chronological and Pathological Aging

2024 . Santinha, Deolinda | Vilaça, Andreia | Estronca, Luís | Schüler, Svenja C. | Bartoli, Catherine | De Sandre-Giovannoli, Annachiara | Figueiredo, Arnaldo | Quaas, Maximillian | Pompe, Tilo | Ori, Alessandro | ferreira, lino

Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging

2023 . Schädel, Patrick | Czapka, Anna | Gebert, Nadja | Jacobsen, Ilse D. | Ori, Alessandro | Werz, Oliver

Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia

IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration

Inflammaging is driven by upregulation of innate immune receptors and systemic interferon signaling and is ameliorated by dietary restriction

2022 . Rasa, Seyed Mohammad Mahdi | Annunziata, Francesco | Krepelova, Anna | Nunna, Suneetha | Omrani, Omid | Gebert, Nadja | Adam, Lisa | Käppel, Sandra | Höhn, Sven | Donati, Giacomo | Jurkowski, Tomasz Piotr | Rudolph, Karl Lenhard | Ori, Alessandro | neri, francesco

Organelle dysfunction and its contribution to metabolic impairments in aging and age-related diseases

2022 . Heiby, Julia C. | Ori, Alessandro

Conserved exchange of paralog proteins during neuronal differentiation

2022 . Di Fraia, Domenico | Anitei, Mihaela | Mackmull, Marie-Therese | Parca, Luca | Behrendt, Laura | Andres-Pons, Amparo | Gilmour, Darren | Helmer-Citterich, Manuela | Kaether, Christoph | Beck, Martin | Ori, Alessandro

Multifaceted Microcephaly-Related Gene MCPH1

2022 . Kristofova, Martina | Ori, Alessandro | Wang, Zhao-Qi

Extensive remodeling of the extracellular matrix during aging contributes to age-dependent impairments of muscle stem cell functionality

2021 . Schüler, Svenja C. | Kirkpatrick, Joanna M. | Schmidt, Manuel | Santinha, Deolinda | Koch, Philipp | Di Sanzo, Simone | Cirri, Emilio | Hemberg, Martin | Ori, Alessandro | von Maltzahn, Julia

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