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G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells

2023 . Cetin, Meryem H. | Rieckmann, Thorsten | Hoffer, Konstantin | Riepen, Britta | Christiansen, Sabrina | Gatzemeier, Fruzsina | Feyerabend, Simon | Schoof, Melanie | Schüller, Ulrich | Petersen, Cordula | Mynarek, Martin | Rothkamm, Kai | Kriegs, Malte | Struve, Nina

The neurological and non-neurological roles of the primary microcephaly-associated protein ASPM

2023 . Wu, Xingxuan | Li, Zheng | Wang, Zhao-Qi | Xu, Xingzhi

Global metabolic alterations in colorectal cancer cells during irinotecan-induced DNA replication stress

2022 . Marx, Christian | Sonnemann, Jürgen | Maddocks, Oliver D. K. | Marx-Blümel, Lisa | Beyer, Mandy | Hoelzer, Doerte | Thierbach, René | Maletzki, Claudia | Linnebacher, Michael | Heinzel, Thorsten | Krämer, Oliver

ASPM promotes ATR-CHK1 activation and stabilizes stalled replication forks in response to replication stress

2022 . WU, Xingxuan | Xu, Shibin | Wang, Peipei | wang, zhao-qi | Chen, Hongxiang | Xu, Xingzhi | PENG, BIN

Partial Reduction in BRCA1 Gene Dose Modulates DNA Replication Stress Level and Thereby Contributes to Sensitivity or Resistance

2022 . Classen, Sandra | Rahlf, Elena | Jungwirth, Johannes | Albers, Nina | Hebestreit, Luca Philipp | Zielinski, Alexandra | Poole, Lena | Groth, Marco | Koch, Philipp | Liehr, Thomas | Kankel, Stefanie | Cordes, Nils | Petersen, Cordula | Rothkamm, Kai | Pospiech, Helmut | Borgmann, Kerstin

RECQ1 Promotes Stress Resistance and DNA Replication Progression Through PARP1 Signaling Pathway in Glioblastoma

2021 . Zhang, Jing | Lian, Hao | Chen, Kui | Pang, Ying | Chen, Mu | Huang, Bingsong | Zhu, Lei | Xu, Siyi | Liu, Min | Zhong, Chunlong

Linking Oxidative Stress and DNA Damage to Changes in the Expression of Extracellular Matrix Components

2021 . Martins, Susana G. | Zilhão, Rita | Thorsteinsdóttir, Sólveig | Carlos, Ana Rita

ATR regulates neuronal activity by modulating presynaptic firing

2021 . Kirtay, Murat | Sell, Josefine | Marx, Christian | Haselmann, Holger | Ceanga, Mihai | Zhou, Zhong-Wei | Rahmati, Vahid | Kirkpatrick, Joanna | Buder, Katrin | Grigaravicius, Paulius | Ori, Alessandro | Geis, Christian | wang, zhao-qi

TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

2016 . Pai, Govind M. | Zielinski, Alexandra | Koalick, Dennis | Ludwig, Kristin | wang, zhao-qi | Borgmann, Kerstin | Pospiech, Helmut | Rubio, Ignacio

DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression

2016 . Hampp, Stephanie | Kiessling, Tina | Buechle, Kerstin | Mansilla, Sabrina F. | Thomale, Jürgen | Rall, Melanie | Ahn, Jinwoo | Gottifredi, Vanesa | Wiesmüller, Lisa | Pospiech, Helmut

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