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Impact of therapeutic inhibition of oncogenic cell signaling tyrosine kinase on cell metabolism: in vivo-detectable metabolic biomarkers of inhibition

2024 . Nath, Kavindra | Gupta, Pradeep K. | Basappa, Johnvesly | Wang, Shengchun | Sen, Neil | Lobello, Cosimo | Tomar, Jyoti S. | Shestov, Alexander A. | Orlovskiy, Stepan | Arias-Mendoza, Fernando | Rauert-Wunderlich, Hilka | Nelson, David S. | Glickson, Jerry D. | Wasik, Mariusz A.

Targeting CXCR4/CXCL12 axis via [177Lu]Lu-DOTAGA.(SA.FAPi)2 with CXCR4 antagonist in triple-negative breast cancer

2024 . Bao, Guangfa | Wang, Ziqiang | Liu, Luoxia | Zhang, Buchuan | Song, Shuang | Wang, Dongdong | Cheng, Siyuan | Moon, Eu-Song | Roesch, Frank | Zhao, Jun | Yu, Bo | Zhu, Xiaohua

Nanoformulation of dasatinib cannot overcome therapy resistance of pancreatic cancer cells with low LYN kinase expression

2024 . Kaul, Marilyn | Sanin, Ahmed Y. | Shi, Wenjie | Janiak, Christoph | Kahlert, Ulf Dietrich

Cytotoxic impact of nicotine products on periodontal ligament cells

2024 . Wiesmann-Imilowski, Nadine | Becker, Philipp | Gielisch, Matthias W. | Ziebolz, Dirk | Vermehren, Franziska | Bitschnau, Marian | Langguth, Nils | Brieger, Jürgen | Deschner, James | Kämmerer, Peer W.

Anti-tumor effects of tirbanibulin in squamous cell carcinoma cells are mediated via disruption of tubulin-polymerization

2024 . DeTemple, Viola K. | Walter, Antje | Bredemeier-Rasche, Sabine | Gutzmer, Ralf | Schaper-Gerhardt, Katrin

Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines

Antineoplastic therapy affects the in vitro phenotype and functionality of healthy human bone marrow-derived mesenchymal stromal cells

2024 . Scherer, Bo | Bogun, Lucienne | Koch, Annemarie | Jäger, Paul | Maus, Uwe | Schmitt, Laura | Krings, Karina S. | Wesselborg, Sebastian | Haas, Rainer | Schroeder, Thomas | Geyh, Stefanie

Complexation of histone deacetylase inhibitor belinostat to Cu(II) prevents premature metabolic inactivation in vitro and demonstrates potent anti-cancer activity in vitro and ex vivo in colon cancer

Chronic senescent human mesenchymal stem cells as possible contributor to the wound healing disorder after exposure to the alkylating agent sulfur mustard

2021 . Rothmiller, Simone | Jäger, Niklas | Meier, Nicole | Meyer, Thimo | Neu, Adrian | Steinritz, Dirk | Thiermann, Horst | Scherer, Michael | Rummel, Christoph | Mangerich, Aswin | Bürkle, Alexander | Schmidt, Annette

Dichloroacetate and PX-478 exhibit strong synergistic effects in a various number of cancer cell lines

2021 . Parczyk, Jonas | Ruhnau, Jérôme | Pelz, Carsten | Schilling, Max | Wu, Hao | Piaskowski, Nicole Nadine | Eickholt, Britta | Kühn, Hartmut | Danker, Kerstin | Klein, Andreas

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