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Study protocol of an open-label, single arm phase II trial investigating the efficacy and safety of Trifluridine/Tipiracil combined with irinotecan as a second line therapy in patients with cholangiocarcinoma (TRITICC)

2023 . Kehmann, Linde | Berres, Marie-Luise | Gonzalez-Carmona, Maria | Modest, Dominik P. | Mohr, Raphael | Wree, Alexander | Venerito, Marino | Strassburg, Christian | Keitel, Verena | Trautwein, Christian | Luedde, Tom | Roderburg, Christoph

A multinational, phase 2, randomised, adaptive protocol to evaluate immunogenicity and reactogenicity of different COVID-19 vaccines in adults ≥75 already vaccinated against SARS-CoV-2 (EU-COVAT-1-AGED): a trial conducted within the VACCELERATE network

2022 . Neuhann, Julia Maria | Stemler, Jannik | Carcas Sansuán, Antonio Javier | Frias Iniesta, Jesus A. | Bethe, Ullrich | Grimm, Sarah | Tischmann, Lea | Zarrouk, Marouan | Cüppers, Arnd | König, Franz | Posch, Martin | Cornely, Oliver

Phase-IIa randomized, double-blind, sham-controlled, parallel group trial on anodal transcranial direct current stimulation (tDCS) over the left and right tempo-parietal junction in autism spectrum disorder—StimAT: study protocol for a clinical trial

Neoadjuvant irradiation of retroperitoneal soft tissue sarcoma with ions (Retro-Ion): study protocol for a randomized phase II pilot trial

2021 . Seidensaal, Katharina | Kieser, M. | Hommertgen, A. | Jaekel, C. | Harrabi, S. B. | Herfarth, K. | Mechtesheimer, G. | Lehner, B. | Schneider, M. | Nienhueser, H. | Fröhling, S. | Egerer, G. | Debus, J. | Uhl, M.

Endoscopic vacuum therapy versus stent treatment of esophageal anastomotic leaks (ESOLEAK): study protocol for a prospective randomized phase 2 trial

2021 . Tachezy, Michael | Chon, Seung-Hun | Rieck, Isabel | Kantowski, Marcus | Christ, Hildegard | Karstens, Karl | Gebauer, Florian | Goeser, Tobias | Rösch, Thomas | Izbicki, Jakob R. | Bruns, Christiane J.

Thoracic radiotherapy plus Durvalumab in elderly and/or frail NSCLC stage III patients unfit for chemotherapy - employing optimized (hypofractionated) radiotherapy to foster durvalumab efficacy: study protocol of the TRADE-hypo trial

2020 . Bozorgmehr, Farastuk | Chung, Inn | Christopoulos, Petros | Krisam, Johannes | Schneider, Marc A. | Brückner, Lena | Mueller, Daniel Wilhelm | Thomas, Michael | Rieken, Stefan

Carbon ion reirradiation compared to intensity-modulated re-radiotherapy for recurrent head and neck cancer (CARE): a randomized controlled trial