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In vitro to in vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmacodynamic models and a multiscale spatial-temporal liver twin

2023 . Dichamp, Jules | Celliere, Géraldine | Ghallab, Ahmed | hassan, reham | Boissier, Noemie | Hofmann, Ute | Reinders, Joerg | Sezgin, Selahaddin | Zuehlke, Sebastian | Hengstler, Jan | Drasdo, Dirk

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity

Newly detected rapid eye movement associated sleep apnea after coronavirus disease 2019 as a possible cause for chronic fatigue: two case reports

2021 . Koczulla, Andreas Rembert | Stegemann, Antje | Gloeckl, Rainer | Winterkamp, Sandra | Sczepanski, Bernd | Boeselt, Tobias | Storre, Jan | Dreher, Michael

Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice

2020 . Schuran, Fenja A. | Lommetz, Christoph | Steudter, Andreas | Ghallab, Ahmed | WIeschendorf, Björn | Schwinge, Dorothee | Zuehlke, Sebastian | Reinders, Joerg | Heeren, Jörg | Lohse, Ansgar W. | Schramm, Christoph | Herkel, Johannes | Carambia, Antonella