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PAPAS promotes differentiation of mammary epithelial cells and suppresses breast carcinogenesis

2024 . Ren, Sijia | Bai, Feng | Schnell, Viviane | Stanko, Clara | Ritsch, Muriel | Schenk, Tino | Barth, Emanuel | Marz, Manja | Wang, Bin | Pei, Xin-Hai | Bierhoff, Holger

Partial Reduction in BRCA1 Gene Dose Modulates DNA Replication Stress Level and Thereby Contributes to Sensitivity or Resistance

2022 . Classen, Sandra | Rahlf, Elena | Jungwirth, Johannes | Albers, Nina | Hebestreit, Luca Philipp | Zielinski, Alexandra | Poole, Lena | Groth, Marco | Koch, Philipp | Liehr, Thomas | Kankel, Stefanie | Cordes, Nils | Petersen, Cordula | Rothkamm, Kai | Pospiech, Helmut | Borgmann, Kerstin

Identification of Ppar γ -modulated miRNA hubs that target the fibrotic tumor microenvironment

2020 . Winkler, Ivana | Bitter, Catrin | Winkler, Sebastian | Weichenhan, Dieter | Thavamani, Abhishek | Hengstler, Jan G. | Borkham-Kamphorst, Erawan | Kohlbacher, Oliver | Plass, Christoph | Geffers, Robert | Weiskirchen, Ralf | Nordheim, Alfred

BRCA1 mislocalization leads to aberrant DNA damage response in heterozygous ABRAXAS1 mutation carrier cells