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The Concept of Stroma AReactive Invasion Front Areas (SARIFA) as a new prognostic biomarker for lipid-driven cancers holds true in pancreatic ductal adenocarcinoma

2024 . Grochowski, Przemyslaw | Grosser, Bianca | Sommer, Florian | Probst, Andreas | Waidhauser, Johanna | Schenkirsch, Gerhard | Reitsam, Nic G. | Märkl, Bruno

Converging deep learning and human-observed tumor-adipocyte interaction as a biomarker in colorectal cancer

2024 . Reitsam, Nic Gabriel | Grosser, Bianca | Steiner, David | Grozdanov, Veselin | Wulczyn, Ellery | L'Imperio, Vincenzo | Plass, Markus | Müller, Heimo | Zatloukal, Kurt | Muti, Hannah S. | Kather, Jakob Nikolas | Märkl, Bruno

SARIFA as a new histopathological biomarker is associated with adverse clinicopathological characteristics, tumor-promoting fatty-acid metabolism, and might predict a metastatic pattern in pT3a prostate cancer

2024 . Enke, Johanna S. | Groß, Matthias | Grosser, Bianca | Sipos, Eva | Steinestel, Julie | Löhr, Phillip | Waidhauser, Johanna | Lapa, Constantin | Märkl, Bruno | Reitsam, Nic G.

The relationship between Stroma AReactive Invasion Front Areas (SARIFA), Warburg-subtype and survival: results from a large prospective series of colorectal cancer patients

2024 . Offermans, Kelly | Reitsam, Nic G. | Simons, Colinda C. J. M. | Grosser, Bianca | Zimmermann, Jessica | Grabsch, Heike I. | Märkl, Bruno | van den Brandt, Piet A.

The SARIFA biomarker in the context of basic research of lipid-driven cancers

2024 . Märkl, Bruno | Reitsam, Nic Gabriel | Grochowski, Przemyslaw | Waidhauser, Johanna | Grosser, Bianca

Stroma AReactive Invasion Front Areas (SARIFA) improves prognostic risk stratification of perioperative chemotherapy treated oesophagogastric cancer patients from the MAGIC and the ST03 trial

2023 . Grosser, Bianca | Emmerson, Jake | Reitsam, Nic Gabriel | Cunningham, David | Nankivell, Matthew | Langley, Ruth | Allum, William H. | Trepel, Martin | Märkl, Bruno | Grabsch, Heike

Novel biomarker SARIFA in colorectal cancer: highly prognostic, not genetically driven and histologic indicator of a distinct tumor biology

2023 . Reitsam, Nic Gabriel | Grozdanov, Veselin | Löffler, Chiara M. L. | Muti, Hannah S. | Grosser, Bianca | Kather, Jakob N. | Märkl, Bruno

Diverse ‘just-right’ levels of chromosomal instability and their clinical implications in neoadjuvant treated gastric cancer