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Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche

2024 . Winter, Susann | Götze, Katharina S. | Hecker, Judith S. | Metzeler, Klaus | Guezguez, Borhane | Woods, Kevin | Medyouf, Hind | Schäffer, Alexander | Schmitz, Marc | Wehner, Rebekka | Glauche, Ingmar | Roeder, Ingo | Rauner, Martina | Hofbauer, Lorenz C. | Platzbecker, Uwe

Age-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in mice

2022 . Suo, Miaomiao | Rommelfanger, Megan | Chen, Yulin | Amro, Elias Moris | Han, Bing | Chen, Zhiyang | Szafranski, Karol | Chakkarappan, Sundaram Reddy | Boehm, Bernhard | MacLean, Adam | Rudolph, Karl Lenhard

Modeling clonal hematopoiesis in umbilical cord blood cells by CRISPR/Cas9

2021 . Christen, Friederike | Hablesreiter, Raphael | Hoyer, Kaja | Hennch, Cornelius | Maluck-Böttcher, Antje | Segler, Angela | Madadi, Annett | Frick, Mareike | Bullinger, Lars | Briest, Franziska | Damm, Frederik

Prevalence and dynamics of clonal hematopoiesis caused by leukemia-associated mutations in elderly individuals without hematologic disorders

2020 . Midic, Danica | Rinke, Jenny | Perner, Florian | Müller, Violetta | Hinze, Anna | Pester, Frank | Landschulze, Jürgen | Ernst, Jana | Gruhn, Bernd | Matziolis, Georg | Heidel, Florian | Hochhaus, Andreas | Ernst, Thomas

ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells