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Impact of plastic-related compounds on the gene expression signature of HepG2 cells transfected with CYP3A4

2023 . Rosellini, Matteo | Omer, Ejlal A. | Schulze, Alicia | Ali, Nadeen T. | Boulos, Joelle C. | Marini, Federico | Küpper, Jan-Heiner | Efferth, Thomas

Investigating the in vitro steatotic mixture effects of similarly and dissimilarly acting test compounds using an adverse outcome pathway-based approach

2021 . Alarcan, Jimmy | de Sousa, Georges | Katsanou, Efrosini S. | Spyropoulou, Anastasia | Batakis, Petros | Machera, Kyriaki | Rahmani, Roger | Lampen, Alfonso | Braeuning, Albert | Lichtenstein, Dajana

Unexpected spotlight on two unusual substances

2021 . Zwirner, Johann | Dreßler, Jan | Gradistanac, Tanja | Möbius, Dustin | Edler, Carolin | Ondruschka, Benjamin

Hepatotoxic pyrrolizidine alkaloids induce DNA damage response in rat liver in a 28-day feeding study

2020 . Ebmeyer,Johanna | Rasinger, Josef Daniel | Hengstler, Jan | Schaudien, Dirk | Creutzenberg,Otto | Lampen, Alfonso | Braeuning, Albert | Hessel-Pras, Stefanie

An adverse outcome pathway for immune-mediated and allergic hepatitis: a case study with the NSAID diclofenac

2020 . Selvaraj, Saravanakumar | Oh, Jung-Hwa | Borlak, Juergen

Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage

2017 . Schenk, Arne | Hofmann, Ute | Schwarz, Michael | Schuppert, Andreas | Braeuning, Albert | Teutonico, Donato | Kuepfer, Lars | Ghallab, Ahmed | Reham, Hassan | Schwen, Lars Ole | Hengstler, Jan G.

Drug‐induced liver injury: results from the hospital‐based Berlin Case–Control Surveillance Study

2014 . Douros, Antonios | Bronder, Elisabeth | Andersohn, Frank | Klimpel, Andreas | Thomae, Michael | Sarganas, Giselle | Kreutz, Reinhold | Garbe, Edeltraut