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Proteasome inhibition enhances the anti-leukemic efficacy of chimeric antigen receptor (CAR) expressing NK cells against acute myeloid leukemia

2024 . Sedloev, David | Chen, Qian | Unglaub, Julia M. | Schanda, Nicola | Hao, Yao | Besiridou, Eleni | Neuber, Brigitte | Schmitt, Anita | Raffel, Simon | Liu, Yi | Janssen, Maike | Müller-Tidow, Carsten | Schmitt, Michael | Sauer, Tim

Potent combination benefit of the AKT inhibitor capivasertib and the BCL-2 inhibitor venetoclax in diffuse large B cell lymphoma

2024 . Willis, Brandon S. | Mongeon, Kevin | Dry, Hannah | Neveras, India L. | Bryan, Nadezda | Pandya, Meghana | Roderick-Richardson, Justine | Xu, Wendan | Yang, Li | Rosen, Alan | Reimer, Corinne | Tuskova, Liliana | Klener, Pavel | Mettetal, Jerome T. | Lenz, Georg | Barry, Simon

Chimeric antigen receptor macrophages targeting c-MET(CAR-M-c-MET) inhibit pancreatic cancer progression and improve cytotoxic chemotherapeutic efficacy

2024 . Zheng, Huaijin | Yang, Xinzhe | Huang, Nan | Yuan, Shangqin | Li, Jiayi | Liu, Xudong | Jiang, Qing | Wu, Shanshan | Ju, Yue | Kleeff, Jorg | Yin, Xiushan | Liao, Quan | Liu, Qiaofei | Zhao, Yupei

PET/CT imaging of head-and-neck and pancreatic cancer in humans by targeting the “Cancer Integrin” αvβ6 with Ga-68-Trivehexin

2021 . Quigley, Neil Gerard | Steiger, Katja | Hoberück, Sebastian | Czech, Norbert | Zierke, Maximilian Alexander | Kossatz, Susanne | Pretze, Marc | Richter, Frauke | Weichert, Wilko | Pox, Christian | Kotzerke, Jörg | Notni, Johannes

Two experts and a newbie: [18F]PARPi vs [18F]FTT vs [18F]FPyPARP—a comparison of PARP imaging agents

2021 . Stotz, Sophie | Kinzler, Johannes | Nies, Anne T. | Schwab, Matthias | Maurer, Andreas

Preclinical evaluation of eltrombopag in a PDX model of myelodysplastic syndromes

Cell spheroids are as effective as single cells suspensions in the treatment of critical-sized bone defects

2021 . Findeisen, Lisa | Bolte, Julia | Vater, Corina | Petzold, Cathleen | Quade, Mandy | Müller, Lars | Goodman, Stuart B. | Zwingenberger, Stefan

A modular and controllable T cell therapy platform for acute myeloid leukemia

Fra-2 overexpression upregulates pro-metastatic cell-adhesion molecules, promotes pulmonary metastasis, and reduces survival in a spontaneous xenograft model of human breast cancer

2021 . Arnold, Sabrina | Kortland, Jan | Maltseva, Diana V. | Nersisyan, Stepan A. | Samatov, Timur R. | Lezius, Susanne | Tonevitsky, Alexander G. | Milde-Langosch, Karin | Wicklein, Daniel | Schumacher, Udo | Stürken, Christine

Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53

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