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Novel pathomechanistic insights into lysosomal storage disorders: how neuron-intrinsic cGAS-STING signaling drives disease progression

2024 . Frosch, Maximilian | Prinz, Marco

GRID1/GluD1 homozygous variants linked to intellectual disability and spastic paraplegia impair mGlu1/5 receptor signaling and excitatory synapses

G protein-mediated signal transduction: a molecular choreography of G protein activation after GTP binding

2024 . Prof. Kostenis, Evi | Jürgenliemke, Lars | Alenfelder, Judith

The many faces of cGAS: how cGAS activation is controlled in the cytosol, the nucleus, and during mitosis

2021 . Herzner, Anna-Maria | Schlee, Martin | Bartok, Eva

Mice Are Not Humans: The Case of p53

2021 . Fischer, Martin

Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density

2021 . Middelkamp, Maximilian | Ruck, Lisa | Krisp, Christoph | Sumisławski, Piotr | Mohammadi, Behnam | Dottermusch, Matthias | Meister, Valerie | Küster, Lukas | Schlüter, Hartmut | Windhorst, Sabine | Neumann, Julia E.

Explaining decisions of graph convolutional neural networks: patient-specific molecular subnetworks responsible for metastasis prediction in breast cancer

2021 . Chereda, Hryhorii | Bleckmann, Annalen | Menck, Kerstin | Perera-Bel, Júlia | Stegmaier, Philip | Auer, Florian | Kramer, Frank | Leha, Andreas | Beißbarth, Tim

Heterogeneous Escape from X Chromosome Inactivation Results in Sex Differences in Type I IFN Responses at the Single Human pDC Level

2020 . Hagen, Sven Hendrik | Henseling, Florian | Hennesen, Jana | Savel, Hélène | Delahaye, Solenne | Richert, Laura | Ziegler, Susanne Maria | Altfeld, Marcus

Merkel cell carcinoma-derived exosome-shuttle miR-375 induces fibroblast polarization by inhibition of RBPJ and p53

2020 . Fan, Kaiji | Spassova, Ivelina | Gravemeyer, Jan | Ritter, Cathrin | Horny, Kai | Lange, Anja | Gambichler, Thilo | Ødum, Niels | Schrama, David | Schadendorf, Dirk | Ugurel, Selma | Becker, Jürgen

Nerve fibers in the tumor microenvironment in neurotropic cancer—pancreatic cancer and cholangiocarcinoma

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