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1000 Titel
  • PTGL: a database for secondary structure-based protein topologies
1000 Autor/in
  1. May, Patrick |
  2. Kreuchwig, Annika |
  3. Steinke, Thomas |
  4. Koch, Ina |
1000 Erscheinungsjahr 2009
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2009-11-10
1000 Erschienen in
1000 Quellenangabe
  • 38(suppl_1): D326-D330
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2009
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1093/nar/gkp980 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808981/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • With growing amount of experimental data, the number of known protein structures also increases continuously. Classification of protein structures helps to understand relationships between protein structure and function. The main classification methods based on secondary structures are SCOP, CATH and TOPS, which all classify under different aspects, and therefore can lead to different results. We developed a mathematically unique representation of protein structure topologies at a higher abstraction level providing new aspects of classification and enabling for a fast search through the data. Protein Topology Graph Library (PTGL; http://ptgl.zib.de) aims at providing a database on protein secondary structure topologies, including search facilities, the visualization as intuitive topology diagrams as well as in the 3D structure, and additional information. Secondary structure-based protein topologies are represented uniquely as undirected labeled graphs in four different ways allowing for exploration under different aspects. The linear notations, and the 2D and 3D diagrams of each notation facilitate a deeper understanding of protein topologies. Several search functions for topologies and sub-topologies, BLAST search possibility, and links to SCOP, CATH and PDBsum support individual and large-scale investigation of protein structures. Currently, PTGL comprises topologies of 54 859 protein structures. Main structural patterns for common structural motifs like TIM-barrel or Jelly Roll are pre-implemented, and can easily be searched.
1000 Sacherschließung
lokal basic local alignment search tool
lokal graphical displays
lokal libraries
lokal protein structure, secondary
lokal anatomy, regional
lokal catheterization
lokal gel
lokal protein structure
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/TWF5LCBQYXRyaWNr|https://frl.publisso.de/adhoc/creator/S3JldWNod2lnLCBBbm5pa2E=|https://frl.publisso.de/adhoc/creator/U3RlaW5rZSwgVGhvbWFz|https://frl.publisso.de/adhoc/creator/S29jaCwgSW5h
1000 Label
1000 Förderer
  1. German Federal Ministry of Education and Research |
  2. Max Planck Society |
1000 Fördernummer
  1. 031392
  2. -
1000 Förderprogramm
  1. FORSYS BMBF grant
  2. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer German Federal Ministry of Education and Research |
    1000 Förderprogramm FORSYS BMBF grant
    1000 Fördernummer 031392
  2. 1000 joinedFunding-child
    1000 Förderer Max Planck Society |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6402773.rdf
1000 Erstellt am 2017-06-02T12:27:46.199+0200
1000 Erstellt von 25
1000 beschreibt frl:6402773
1000 Bearbeitet von 218
1000 Zuletzt bearbeitet Thu Aug 18 08:01:37 CEST 2022
1000 Objekt bearb. Fri Jul 23 13:49:30 CEST 2021
1000 Vgl. frl:6402773
1000 Oai Id
  1. oai:frl.publisso.de:frl:6402773 |
1000 Sichtbarkeit Metadaten public
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