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Genome Res.-2011-Heidel-1882-91.pdf 714,36KB
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1000 Titel
  • Phylogeny-wide analysis of social amoeba genomes highlights ancient origins for complex intercellular communication
1000 Autor/in
  1. Heidel, Andrew J. |
  2. Lawal, Hajara M. |
  3. Felder, Marius |
  4. Schilde, Christina |
  5. Helps, Nicholas R. |
  6. Tunggal, Budi |
  7. Rivero, Francisco |
  8. John, Uwe |
  9. Schleicher, Michael |
  10. Eichinger, Ludwig |
  11. Noegel, Angelika A. |
  12. Schaap, Pauline |
  13. Platzer, Matthias |
  14. Glöckner, Gernot |
1000 Erscheinungsjahr 2011
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2011-07-14
1000 Erschienen in
1000 Quellenangabe
  • 21: 1882-1891
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2011
1000 Lizenz
1000 Verlagsversion
  • https://dx.doi.org/10.1101/gr.121137.111 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205573/ |
1000 Ergänzendes Material
  • http://genome.cshlp.org/content/21/11/1882/suppl/DC1 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Dictyostelium discoideum (DD), an extensively studied model organism for cell and developmental biology, belongs to the most derived group 4 of social amoebas, a clade of altruistic multicellular organisms. To understand genome evolution over long time periods and the genetic basis of social evolution, we sequenced the genomes of Dictyostelium fasciculatum (DF) and Polysphondylium pallidum (PP), which represent the early diverging groups 1 and 2, respectively. In contrast to DD, PP and DF have conventional telomere organization and strongly reduced numbers of transposable elements. The number of protein-coding genes is similar between species, but only half of them comprise an identifiable set of orthologous genes. In general, genes involved in primary metabolism, cytoskeletal functions and signal transduction are conserved, while genes involved in secondary metabolism, export, and signal perception underwent large differential gene family expansions. This most likely signifies involvement of the conserved set in core cell and developmental mechanisms, and of the diverged set in niche- and species-specific adaptations for defense and food, mate, and kin selection. Phylogenetic dating using a concatenated data set and extensive loss of synteny indicate that DF, PP, and DD split from their last common ancestor at least 0.6 billion years ago.
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/SGVpZGVsLCBBbmRyZXcgSi4=|https://frl.publisso.de/adhoc/creator/TGF3YWwsIEhhamFyYSBNLg==|https://frl.publisso.de/adhoc/creator/RmVsZGVyLCBNYXJpdXM=|https://frl.publisso.de/adhoc/creator/U2NoaWxkZSwgQ2hyaXN0aW5h|https://frl.publisso.de/adhoc/creator/SGVscHMsIE5pY2hvbGFzIFIu|https://frl.publisso.de/adhoc/creator/VHVuZ2dhbCwgQnVkaQ==|https://frl.publisso.de/adhoc/creator/Uml2ZXJvLCBGcmFuY2lzY28=|https://frl.publisso.de/adhoc/creator/Sm9obiwgVXdl|https://frl.publisso.de/adhoc/creator/U2NobGVpY2hlciwgTWljaGFlbA==|https://frl.publisso.de/adhoc/creator/RWljaGluZ2VyLCBMdWR3aWc=|https://frl.publisso.de/adhoc/creator/Tm9lZ2VsLCBBbmdlbGlrYSBBLg==|https://frl.publisso.de/adhoc/creator/U2NoYWFwLCBQYXVsaW5l|http://orcid.org/0000-0003-0596-8582|http://orcid.org/0000-0002-9061-1061
1000 Label
1000 Förderer
  1. DFG |
  2. BBSRC |
1000 Fördernummer
  1. Gl235/1; NO113/18
  2. BB/E016308/
1000 Förderprogramm
  1. -
  2. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer DFG |
    1000 Förderprogramm -
    1000 Fördernummer Gl235/1; NO113/18
  2. 1000 joinedFunding-child
    1000 Förderer BBSRC |
    1000 Förderprogramm -
    1000 Fördernummer BB/E016308/
1000 Objektart article
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1000 @id frl:6402940.rdf
1000 Erstellt am 2017-06-08T10:23:10.003+0200
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1000 Bearbeitet von 218
1000 Zuletzt bearbeitet Fri Nov 27 12:48:59 CET 2020
1000 Objekt bearb. Fri Nov 27 12:48:58 CET 2020
1000 Vgl. frl:6402940
1000 Oai Id
  1. oai:frl.publisso.de:frl:6402940 |
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