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1000 Titel
  • Effects of Different Oral Doses of Sodium Chloride on the Basal Acid-Base and Mineral Status of Exercising Horses Fed Low Amounts of Hay
1000 Autor/in
  1. Zeyner, Annette |
  2. Romanowski, Kristin |
  3. Vernunft, Andreas |
  4. Harris, Patricia |
  5. Müller, Ann-Marie |
  6. Wolf, Carola |
  7. Kienzle, Ellen |
1000 Erscheinungsjahr 2017
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2017-01-03
1000 Erschienen in
1000 Quellenangabe
  • 12(1):e0168325
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2017
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1000 Verlagsversion
  • http://dx.doi.org/10.1371/journal.pone.0168325 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207637/ |
1000 Ergänzendes Material
  • http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168325#sec026 |
1000 Publikationsstatus
1000 Begutachtungsstatus
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1000 Abstract/Summary
  • The provision of NaCl, according to current recommendations, to horses in moderate work has been shown to induce immediate postprandial acidosis. The present study aimed to clarify whether this NaCl induced acidosis i) persists beyond the immediate postprandial period, and ii) is still present after a 2 week adaptation period. Six adult warmblood mares in moderate work received daily 1.00 kg hay per 100 kg body weight (bwt) only together with 0.64 kg unprocessed cereal grains/100 kg bwt.d as fed basis. Using a 3x3 Latin Square, either 0 (NaCl-0), 50 (NaCl-50) or 100 (NaCl-100) g NaCl/d were fed together with the concentrates in two equal doses for 3 weeks. During the final week, a mineral digestibility trial was undertaken. The middle sodium and chloride intake (NaCl-50) at least met the most common recommendations for moderate work. Morning (7:00 AM) urine and venous blood samples were collected on days 0, 1–4, 8, and 15, and analysed for pH, acid-base status, creatinine and electrolyte concentrations. Fractional electrolyte clearances (FC) were determined. Mean apparent sodium digestibility ranged between 60–62% whereas chloride digestibility was consistently above 94%. Supplementing 100 g but not 50 g of NaCl resulted in significant reduction of blood pH and base excess as well as urinary pH and urine acid excretion. Both 50 g and 100 g NaCl supplementation caused a significant reduction in base and net acid-base excretion, urine density and potassium concentration, but increased urine sodium concentration and the FC of sodium and chloride (P < 0.05). This suggests that a high proportion of the recommended salt doses is excreted renally. The above effects of NaCl supplementation persisted over the 2 week measurement period. Results suggest that feeding 100 g NaCl to moderately exercising horses results in mild metabolic acidosis, whereas feeding 50 g according to current recommendations resulted in compensated acidosis.
1000 Sacherschließung
lokal Blood
lokal Excretion
lokal Urine
lokal Acidosis
lokal Horses
lokal Sodium chloride
lokal Diet
lokal Chlorides
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  1. WALTHAM Centre for Pat Nutrition |
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    1000 Förderer WALTHAM Centre for Pat Nutrition |
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1000 Erstellt am 2017-06-09T11:42:08.735+0200
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