Download
srep22084.pdf 397,45KB
WeightNameValue
1000 Titel
  • Risk of second primary cancers in multiple myeloma survivors in German and Swedish cancer registries
1000 Autor/in
  1. Chen, Tianhui |
  2. Fallah, Mahdi |
  3. Brenner, Hermann |
  4. Jansen, Lina |
  5. Mai, Elias K. |
  6. Castro, Felipe A. |
  7. Katalinic, Alexander |
  8. Emrich, Katharina |
  9. Holleczek, Bernd |
  10. Geiss, Karla |
  11. Eberle, Andrea |
  12. Sundquist, Kristina |
  13. Hemminki, Kari |
1000 Mitwirkende/r
  1. GEKID Cancer Survival Working Group |
1000 Erscheinungsjahr 2016
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2016-02-24
1000 Erschienen in
1000 Quellenangabe
  • 6:22084
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2016
1000 Lizenz
1000 Verlagsversion
  • http://dx.doi.org/10.1038/srep22084 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764950/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • We aimed at investigating the distribution and risk of second primary cancers (SPCs) in multiple myeloma (MM) survivors in Germany and Sweden to provide etiological understanding of SPCs and insight into their incidence rates and recording practices. MM patients diagnosed in 1997-2010 at age >/=15 years were selected from the Swedish (nationwide) and 12 German cancer registries. Standardized incidence ratios (SIRs) were used to assess risk of a specific SPC compared to risk of the same first cancer in the corresponding background population. Among 18,735 survivors of first MM in Germany and 7,560 in Sweden, overall 752 and 349 SPCs were recorded, respectively. Significantly elevated SIRs of specific SPCs were observed for acute myeloid leukemia (AML; SIR = 4.9) in Germany and for kidney cancer (2.3), AML (2.3) and nervous system cancer (1.9) in Sweden. Elevated risk for AML was more pronounced in the earlier diagnosis period compared to the later, i.e., 9.7 (4.2-19) for 1997-2003 period versus 3.5 (1.5-6.9) for 2004-2010 in Germany; 3.8 (1.4-8.3) for 1997-2003 versus 2.2 (0.3-7.8) for 2004-2010 in Sweden. We found elevated risk for AML for overall, early diagnosis periods and longer follow-up times in both populations, suggesting possible side effects of treatment for MM patients.
1000 Sacherschließung
lokal Cancer epidemiology
lokal Myeloma
lokal Epidemiology
1000 Fachgruppe
  1. Medizin |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/Q2hlbiwgVGlhbmh1aQ==|https://frl.publisso.de/adhoc/creator/RmFsbGFoLCBNYWhkaQ==|https://frl.publisso.de/adhoc/creator/QnJlbm5lciwgSGVybWFubg==|https://frl.publisso.de/adhoc/creator/SmFuc2VuLCBMaW5h|https://frl.publisso.de/adhoc/creator/TWFpLCBFbGlhcyBLLg==|https://frl.publisso.de/adhoc/creator/Q2FzdHJvLCBGZWxpcGUgQS4=|https://frl.publisso.de/adhoc/creator/S2F0YWxpbmljLCBBbGV4YW5kZXI=|https://frl.publisso.de/adhoc/creator/RW1yaWNoLCBLYXRoYXJpbmE=|https://frl.publisso.de/adhoc/creator/SG9sbGVjemVrLCBCZXJuZA==|https://frl.publisso.de/adhoc/creator/R2Vpc3MsIEthcmxh|https://frl.publisso.de/adhoc/creator/RWJlcmxlLCBBbmRyZWE=|https://frl.publisso.de/adhoc/creator/U3VuZHF1aXN0LCBLcmlzdGluYQ==|https://frl.publisso.de/adhoc/creator/SGVtbWlua2ksIEthcmk=|https://frl.publisso.de/adhoc/contributor/R0VLSUQgQ2FuY2VyIFN1cnZpdmFsIFdvcmtpbmcgR3JvdXA=
1000 Förderer
  1. German Cancer Aid (Deutsche Krebshilfe) |
1000 Fördernummer
  1. 108257; 110446
1000 Förderprogramm
  1. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer German Cancer Aid (Deutsche Krebshilfe) |
    1000 Förderprogramm -
    1000 Fördernummer 108257; 110446
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6403978.rdf
1000 Erstellt am 2017-08-18T09:56:29.674+0200
1000 Erstellt von 122
1000 beschreibt frl:6403978
1000 Bearbeitet von 218
1000 Zuletzt bearbeitet Mon Jun 18 13:17:49 CEST 2018
1000 Objekt bearb. Mon Jun 18 13:17:48 CEST 2018
1000 Vgl. frl:6403978
1000 Oai Id
  1. oai:frl.publisso.de:frl:6403978 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

View source