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WeightNameValue
1000 Titel
  • Accuracy of the unified approach in maternally influenced traits - illustrated by a simulation study in the honey bee (Apis mellifera)
1000 Autor/in
  1. Gupta, Pooja |
  2. Reinsch, Norbert |
  3. Spötter, Andreas |
  4. Conrad, Tim |
  5. Bienefeld, Kaspar |
1000 Erscheinungsjahr 2013
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2013-05-06
1000 Erschienen in
1000 Quellenangabe
  • 14: 36
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2013
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/1471-2156-14-36 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654974/ |
1000 Ergänzendes Material
  • https://bmcgenet.biomedcentral.com/articles/10.1186/1471-2156-14-36#Declarations |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: The honey bee is an economically important species. With a rapid decline of the honey bee population, it is necessary to implement an improved genetic evaluation methodology. In this study, we investigated the applicability of the unified approach and its impact on the accuracy of estimation of breeding values for maternally influenced traits on a simulated dataset for the honey bee. Due to the limitation to the number of individuals that can be genotyped in a honey bee population, the unified approach can be an efficient strategy to increase the genetic gain and to provide a more accurate estimation of breeding values. We calculated the accuracy of estimated breeding values for two evaluation approaches, the unified approach and the traditional pedigree based approach. We analyzed the effects of different heritabilities as well as genetic correlation between direct and maternal effects on the accuracy of estimation of direct, maternal and overall breeding values (sum of maternal and direct breeding values). The genetic and reproductive biology of the honey bee was accounted for by taking into consideration characteristics such as colony structure, uncertain paternity, overlapping generations and polyandry. In addition, we used a modified numerator relationship matrix and a realistic genome for the honey bee. RESULTS: For all values of heritability and correlation, the accuracy of overall estimated breeding values increased significantly with the unified approach. The increase in accuracy was always higher for the case when there was no correlation as compared to the case where a negative correlation existed between maternal and direct effects. CONCLUSIONS: Our study shows that the unified approach is a useful methodology for genetic evaluation in honey bees, and can contribute immensely to the improvement of traits of apicultural interest such as resistance to Varroa or production and behavioural traits. In particular, the study is of great interest for cases where negative correlation between maternal and direct effects and uncertain paternity exist, thus, is of relevance for other species as well. The study also provides an important framework for simulating genomic and pedigree datasets that will prove to be helpful for future studies.
1000 Sacherschließung
lokal Single-step approach
lokal Single nucleotide polymorphism
lokal Genetic evaluation
lokal Maternal effects
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/R3VwdGEsIFBvb2ph|https://frl.publisso.de/adhoc/creator/UmVpbnNjaCwgTm9yYmVydA==|https://frl.publisso.de/adhoc/creator/U3DDtnR0ZXIsIEFuZHJlYXM=|https://frl.publisso.de/adhoc/creator/Q29ucmFkLCBUaW0=|https://frl.publisso.de/adhoc/creator/QmllbmVmZWxkLCBLYXNwYXI=
1000 Label
1000 Förderer
  1. German Federal Ministry of Food, Agriculture and Consumer Protection (BMELV) |
1000 Fördernummer
  1. 2808HS009
1000 Förderprogramm
  1. Project "Marker assisted selection of Varroa-tolerant honey bees"
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer German Federal Ministry of Food, Agriculture and Consumer Protection (BMELV) |
    1000 Förderprogramm Project "Marker assisted selection of Varroa-tolerant honey bees"
    1000 Fördernummer 2808HS009
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6404584.rdf
1000 Erstellt am 2017-09-22T11:49:34.388+0200
1000 Erstellt von 218
1000 beschreibt frl:6404584
1000 Bearbeitet von 288
1000 Zuletzt bearbeitet 2021-03-30T11:24:31.336+0200
1000 Objekt bearb. Tue Mar 30 11:24:30 CEST 2021
1000 Vgl. frl:6404584
1000 Oai Id
  1. oai:frl.publisso.de:frl:6404584 |
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