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1000 Titel
  • Oral cancer via the bargain bin: The risk of oral cancer associated with a smokeless tobacco product (Naswar)
1000 Autor/in
  1. Khan, Sheraz |
  2. Dreger, Steffen |
  3. Shah, Syed Majid Hussain |
  4. Pohlabeln, Hermann |
  5. Khan, Zohaib |
  6. Ullah, Zakir |
  7. Rehman, Basheer |
  8. Zeeb, Hajo |
1000 Erscheinungsjahr 2017
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2017-07-10
1000 Erschienen in
1000 Quellenangabe
  • 12(7):e0180445
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2017
1000 Lizenz
1000 Verlagsversion
  • http://dx.doi.org/10.1371/journal.pone.0180445 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503251/ |
1000 Ergänzendes Material
  • http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180445#sec033 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • In the wake of smokeless tobacco (SLT) being advocated as a mean of tobacco harm reduction, it is pertinent to establish individual health risks associated with each SLT product. This case-control study was aimed at assessing the risk of oral cancer associated with a smokeless tobacco product (Naswar). The study was conducted from September 2014 till May 2015 in Khyber Pakhtunkhwa, Pakistan. Exposure and covariate information was collected through a structured questionnaire. Conditional logistic regression was used to calculate odds ratios (OR) along with their 95% confidence intervals (CI). 84 oral cancer cases (62% males) and 174 age- and sex-matched controls were recruited. Ever users of Naswar had more than a 20-fold higher risk of oral cancer compared to never-users (OR 21.2, 95% CI 8.4–53.8). Females had a higher risk of oral cancer with the use of Naswar (OR 29.0, 95% CI 5.4–153.9) as compared to males (OR 21.0, 95% CI 6.1–72.1). Based on this result, 68% (men) and 38% (women) of the oral cancer burden in Pakistan is attributable to Naswar. The risk estimates observed in this study are comparable to risk estimates reported by previous studies on other forms of SLT use and the risk of oral cancer in Pakistan. The exposure-response relationship also supports a strong role of Naswar in the etiology of oral cancer in Pakistan. Although still requiring further validation through independent studies, these findings may be used for smokeless tobacco control in countries where Naswar use is common.
1000 Sacherschließung
lokal habits
lokal Pakistan
lokal Asia
lokal cancer detection and diagnosis
lokal cancer risk factors
lokal alcohol consumption
lokal smoking habits
lokal case-control studies
1000 Fachgruppe
  1. Medizin |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/S2hhbiwgU2hlcmF6|https://frl.publisso.de/adhoc/creator/RHJlZ2VyLCBTdGVmZmVu|https://frl.publisso.de/adhoc/creator/U2hhaCwgU3llZCBNYWppZCBIdXNzYWlu|http://orcid.org/0000-0002-9575-1119|http://orcid.org/0000-0002-1885-8254|https://frl.publisso.de/adhoc/creator/VWxsYWgsIFpha2ly|https://frl.publisso.de/adhoc/creator/UmVobWFuLCBCYXNoZWVy|http://orcid.org/0000-0001-7509-242X
1000 Label
1000 Förderer
  1. Leibniz Institute for Prevention Research and Epidemiology - BIPS GmbH, Bremen, Germany |
  2. Leibniz Association |
1000 Fördernummer
  1. -
  2. -
1000 Förderprogramm
  1. internal funding
  2. Open Access fund
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Leibniz Institute for Prevention Research and Epidemiology - BIPS GmbH, Bremen, Germany |
    1000 Förderprogramm internal funding
    1000 Fördernummer -
  2. 1000 joinedFunding-child
    1000 Förderer Leibniz Association |
    1000 Förderprogramm Open Access fund
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6404596.rdf
1000 Erstellt am 2017-09-22T12:37:19.365+0200
1000 Erstellt von 122
1000 beschreibt frl:6404596
1000 Bearbeitet von 291
1000 Zuletzt bearbeitet Thu Jan 30 23:21:19 CET 2020
1000 Objekt bearb. Fri Jun 01 13:39:45 CEST 2018
1000 Vgl. frl:6404596
1000 Oai Id
  1. oai:frl.publisso.de:frl:6404596 |
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