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Percutaneous Disc Decompression with Nucleoplasty–Volumetry of the Nucleus Pulposus Using Ultrahigh-Field MRI

  1. Kasch, Richard
  2. Mensel, Birger
  3. Schmidt, Florian
  4. Drescher, Wolf
  5. Pfuhl, Ralf
  6. Ruetten, Sebastian
  7. Merk, Harry R.
  8. Kayser, Ralph

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WeightNameValue
1000 Titel
  • Percutaneous Disc Decompression with Nucleoplasty–Volumetry of the Nucleus Pulposus Using Ultrahigh-Field MRI
1000 Autor/in
  1. Kasch, Richard |
  2. Mensel, Birger |
  3. Schmidt, Florian |
  4. Drescher, Wolf |
  5. Pfuhl, Ralf |
  6. Ruetten, Sebastian |
  7. Merk, Harry R. |
  8. Kayser, Ralph |
1000 Erscheinungsjahr 2012
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2012-07-25
1000 Erschienen in
1000 Quellenangabe
  • 7(7): e41497
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2012
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1371/journal.pone.0041497 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405080/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • PURPOSE: To evaluate changes in nucleus pulposus volume as a potential parameter for the effects of disc decompression. METHODS: Fifty-two discs (T8 to L1) were extracted from 26 pigs and separated into thoracic (T8 to T11) and thoracolumbar discs (T12 to L1). The discs were imaged using 7.1 Tesla ultrahigh-field magnetic resonance imaging (MRI) with acquisition of axial T2-weighted turbo spin-echo sequences for determination of baseline and postinterventional nucleus pulposus volumes. Volumes were calculated using OsiriX® (http://www.osirix-viewer.com). After randomization, one group was treated with nucleoplasty, while the placebo group was treated with an identical procedure but without coblation current. The readers analyzing the MR images were blinded to the kind of procedure performed. Baseline and postinterventional volumes were compared between the nucleoplasty and placebo group. RESULTS: Average preinterventional nucleus volume was 0.799 (SD: 0.212) ml. Postinterventional volume reduction in the nucleoplasty group was significant at 0.052 (SD: 0.035) ml or 6.30% (p<0.0001) (thoracic discs) and 0.082 (SD: 0.042) ml or 7.25% (p = 0.0078) (thoracolumbar discs). Nucleoplasty achieved volume reductions of 0.114 (SD: 0.054) ml or 14.72% (thoracic) and 0.093 (SD: 0.081) ml or 11.61% (thoracolumbar) compared with the placebo group. CONCLUSIONS: Nucleoplasty significantly reduces thoracic and thoracolumbar nucleus pulposus volumes in porcine discs.
1000 Sacherschließung
lokal Animal slaughter
lokal Sequence analysis
lokal Spine
lokal Sheep
lokal Magnetic resonance imaging
lokal Soft tissues
lokal Image analysis
lokal Swine
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/S2FzY2gsIFJpY2hhcmQ=|https://frl.publisso.de/adhoc/creator/TWVuc2VsLCBCaXJnZXI=|https://frl.publisso.de/adhoc/creator/U2NobWlkdCwgRmxvcmlhbg==|https://frl.publisso.de/adhoc/creator/RHJlc2NoZXIsIFdvbGY=|https://frl.publisso.de/adhoc/creator/UGZ1aGwsIFJhbGY=|https://frl.publisso.de/adhoc/creator/UnVldHRlbiwgU2ViYXN0aWFu|https://frl.publisso.de/adhoc/creator/TWVyaywgSGFycnkgUi4=|https://frl.publisso.de/adhoc/creator/S2F5c2VyLCBSYWxwaA==
1000 Label
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  1. AArthroCare Deutschland, Remscheid |
1000 Fördernummer
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1000 Förderprogramm
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1000 Dateien
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    1000 Förderer AArthroCare Deutschland, Remscheid |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
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1000 @id frl:6404669.rdf
1000 Erstellt am 2017-09-26T09:37:41.509+0200
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1000 Bearbeitet von 288
1000 Zuletzt bearbeitet Tue Mar 30 11:40:46 CEST 2021
1000 Objekt bearb. Tue Mar 30 11:40:46 CEST 2021
1000 Vgl. frl:6404669
1000 Oai Id
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