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1000 Titel
  • Interference of stress with the somatotropic axis in pigs – lights on new biomarkers
1000 Autor/in
  1. Wirthgen, Elisa |
  2. Kunze, Martin |
  3. Goumon, Sébastien |
  4. Walz, Christina |
  5. Höflich, Christine |
  6. Spitschak, Marion |
  7. Brenmoehl, Julia |
  8. Kanitz, Ellen |
  9. Tuchscherer, Margret |
  10. Otten, Winfried |
  11. Schön, Peter |
  12. Manteuffel, Christian |
  13. Tuchscherer, Armin |
  14. Pfuhl, Ralf |
  15. Metges, Cornelia C. |
  16. Stabenow, Bernd |
  17. Erdmann, Sandra |
  18. Schluricke, Kathleen |
  19. Faucitano, Luigi |
  20. Gimsa, Ulrike |
  21. Hoeflich, Andreas |
1000 Erscheinungsjahr 2017
1000 LeibnizOpen
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2017-09-21
1000 Erschienen in
1000 Quellenangabe
  • 7:12055
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2017
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1038/s41598-017-11521-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608691/ |
1000 Ergänzendes Material
  • https://www.nature.com/articles/s41598-017-11521-5#Sec20 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • The acceptance of animal products is increasingly associated with standardized animal welfare, which relates to appropriate animal husbandry from birth to slaughter. In particular, shipment to the slaughterhouse is considered as a critical process exposing the animals to a number of, in part severe, stressors. New biomarkers may be useful for the assessment of animal welfare. The IGF-system has been assessed in a commercial pig transport in conjunction with established markers of stress response. Furthermore, the effect of repeated restraint as an experimental model for repeated acute stress was investigated. During shipment from farm to slaughterhouse, plasma concentrations of IGFBP-3 and IGFBP-2 were significantly reduced (p < 0.01). After shipment, the plasma concentrations of IGFBP-5, glucocorticoids and IL-2 increased but decreased after lairage (p < 0.05) whereas IGF-1 decreased after shipment (p < 0.01). Repeated acute stress increased concentrations of IGFBP-3 and IGF-1 in exsanguination blood (p < 0.05). Differential IGF- signatures can indicate altered endocrine or metabolic control and thus contain complex animal-related information. The somatotropic axis may be of particular interest when established biomarkers such as cortisol, glucose, or lactate cannot be used for the assessment of animal stress or welfare.
1000 Sacherschließung
lokal Physiology
lokal Endocrine system and metabolic diseases
1000 Fachgruppe
  1. Biologie |
  2. Agrarwissenschaften |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/V2lydGhnZW4sIEVsaXNh|https://frl.publisso.de/adhoc/creator/S3VuemUsIE1hcnRpbg==|https://frl.publisso.de/adhoc/creator/R291bW9uLCBTw6liYXN0aWVu|https://frl.publisso.de/adhoc/creator/V2FseiwgQ2hyaXN0aW5h|https://frl.publisso.de/adhoc/creator/SMO2ZmxpY2gsIENocmlzdGluZQ==|https://frl.publisso.de/adhoc/creator/U3BpdHNjaGFrLCBNYXJpb24=|https://frl.publisso.de/adhoc/creator/QnJlbm1vZWhsLCBKdWxpYQ==|https://frl.publisso.de/adhoc/creator/S2FuaXR6LCBFbGxlbg==|https://frl.publisso.de/adhoc/creator/VHVjaHNjaGVyZXIsIE1hcmdyZXQ=|https://frl.publisso.de/adhoc/creator/T3R0ZW4sIFdpbmZyaWVk|https://frl.publisso.de/adhoc/creator/U2Now7ZuLCBQZXRlcg==|https://frl.publisso.de/adhoc/creator/TWFudGV1ZmZlbCwgQ2hyaXN0aWFu|https://frl.publisso.de/adhoc/creator/VHVjaHNjaGVyZXIsIEFybWlu|https://frl.publisso.de/adhoc/creator/UGZ1aGwsIFJhbGY=|https://frl.publisso.de/adhoc/creator/TWV0Z2VzLCBDb3JuZWxpYSBDLg==|https://frl.publisso.de/adhoc/creator/U3RhYmVub3csIEJlcm5k|https://frl.publisso.de/adhoc/creator/RXJkbWFubiwgU2FuZHJh|https://frl.publisso.de/adhoc/creator/U2NobHVyaWNrZSwgS2F0aGxlZW4=|https://frl.publisso.de/adhoc/creator/RmF1Y2l0YW5vLCBMdWlnaQ==|http://orcid.org/0000-0003-2248-5793|http://orcid.org/0000-0003-2018-2836
1000 Label
1000 Förderer
  1. Leibniz Association |
  2. Leibniz Institute for Farm Animal Biology (FBN) |
1000 Fördernummer
  1. -
  2. -
1000 Förderprogramm
  1. Open Access Fund
  2. Open Access Fund
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Leibniz Association |
    1000 Förderprogramm Open Access Fund
    1000 Fördernummer -
  2. 1000 joinedFunding-child
    1000 Förderer Leibniz Institute for Farm Animal Biology (FBN) |
    1000 Förderprogramm Open Access Fund
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6406185.rdf
1000 Erstellt am 2018-01-05T13:33:54.696+0100
1000 Erstellt von 122
1000 beschreibt frl:6406185
1000 Bearbeitet von 218
1000 Zuletzt bearbeitet Thu Jan 30 16:13:07 CET 2020
1000 Objekt bearb. Mon May 28 10:18:23 CEST 2018
1000 Vgl. frl:6406185
1000 Oai Id
  1. oai:frl.publisso.de:frl:6406185 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
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