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WeightNameValue
1000 Titel
  • Impact of chronic and acute academic stress on lymphocyte subsets and monocyte function
1000 Autor/in
  1. Maydych, Viktoriya |
  2. Claus, Maren |
  3. Dychus, Nicole |
  4. Ebel, Melanie |
  5. Damaschke, Jürgen |
  6. Diestel, Stefan |
  7. Wolf, Oliver T. |
  8. Kleinsorge, Thomas |
  9. Watzl, Carsten |
1000 Erscheinungsjahr 2017
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2017-11-16
1000 Erschienen in
1000 Quellenangabe
  • 12(11):e0188108
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2017
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1371/journal.pone.0188108 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690587/ |
1000 Ergänzendes Material
  • http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0188108#sec020 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • This study investigated the effects of a temporally confined naturalistic stressor (academic stress) on immune functions. Furthermore, moderating influences of a number of psychological variables were assessed. Five blood samples were obtained from 20 students during an observation period of 8 weeks, starting 4.5 weeks before an exam period up to 1 week following the last exam. The analysis of 45 immune parameters revealed several time-dependent changes attributable to examination stress. We observed a reduction in the absolute numbers of natural killer (NK) cells and monocytes in peripheral blood and a shift towards more immature and naïve cells within NK and T cell populations. In addition, IL-6 and TNF-α production by LPS-stimulated monocytes was increased. Psychological variables were grouped by means of factor analyses into two factors. One factor, which was interpreted as an indication of chronic stress, moderated the relationships between academic stress and percentages of mature CD57+ NK cells. This chronic stress factor was also associated with an increase in memory and a decrease in naïve CD8 T cells and increased serum levels of IL-17. The present study identifies important potential psychological mediators of stress-induced changes in specific immunological parameters.
1000 Sacherschließung
lokal Monocytes
lokal Emotions
lokal NK cells
lokal Psychological stress
lokal Cortisol
lokal Cytotoxic T cells
lokal Psychometrics
lokal T cells
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/TWF5ZHljaCwgVmlrdG9yaXlh|http://orcid.org/0000-0001-8732-0645|https://frl.publisso.de/adhoc/uri/RHljaHVzLCBOaWNvbGU=|https://frl.publisso.de/adhoc/uri/RWJlbCwgTWVsYW5pZQ==|https://frl.publisso.de/adhoc/creator/RGFtYXNjaGtlLCBKw7xyZ2Vu|https://frl.publisso.de/adhoc/uri/RGllc3RlbCwgU3RlZmFu|https://frl.publisso.de/adhoc/creator/V29sZiwgT2xpdmVyIFQu|http://d-nb.info/gnd/115286268|http://orcid.org/0000-0001-5195-0995
1000 Label
1000 Förderer
  1. Leibniz-Gemeinschaft |
1000 Fördernummer
  1. -
1000 Förderprogramm
  1. Open Access Fund
1000 Dateien
  1. Impact of chronic and acute academic stress on lymphocyte subsets and monocyte function
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Leibniz-Gemeinschaft |
    1000 Förderprogramm Open Access Fund
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6406463.rdf
1000 Erstellt am 2018-01-24T15:54:14.917+0100
1000 Erstellt von 254
1000 beschreibt frl:6406463
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Mon Nov 30 14:35:47 CET 2020
1000 Objekt bearb. Mon Nov 30 14:35:46 CET 2020
1000 Vgl. frl:6406463
1000 Oai Id
  1. oai:frl.publisso.de:frl:6406463 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
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