Genome analyses of the sunflower pathogen Plasmopara halstedii provide insights into effector evolution in downy mildews and Phytophthora

  1. SHARMA, RAHUL ORCID logo
  2. Xia, Xiaojuan
  3. Cano, Liliana M.
  4. Evangelisti, Edouard
  5. Kemen, Eric
  6. Judelson, Howard
  7. Oome, Stan
  8. Sambles, Christine
  9. van den Hoogen, D. Johan
  10. Kitner, Miloslav
  11. Klein, Joël
  12. Meijer, Harold J. G.
  13. Spring, Otmar
  14. Win, Joe
  15. Zipper, Reinhard
  16. Bode, Helge B.
  17. Govers, Francine
  18. Kamoun, Sophien
  19. Schornack, Sebastian
  20. Studholme, David J.
  21. Van den Ackerveken, Guido
  22. Thines, Marco

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1000 Titel
  • Genome analyses of the sunflower pathogen Plasmopara halstedii provide insights into effector evolution in downy mildews and Phytophthora
1000 Autor/in
  1. SHARMA, RAHUL |
  2. Xia, Xiaojuan |
  3. Cano, Liliana M. |
  4. Evangelisti, Edouard |
  5. Kemen, Eric |
  6. Judelson, Howard |
  7. Oome, Stan |
  8. Sambles, Christine |
  9. van den Hoogen, D. Johan |
  10. Kitner, Miloslav |
  11. Klein, Joël |
  12. Meijer, Harold J. G. |
  13. Spring, Otmar |
  14. Win, Joe |
  15. Zipper, Reinhard |
  16. Bode, Helge B. |
  17. Govers, Francine |
  18. Kamoun, Sophien |
  19. Schornack, Sebastian |
  20. Studholme, David J. |
  21. Van den Ackerveken, Guido |
  22. Thines, Marco |
1000 Erscheinungsjahr 2015
1000 LeibnizOpen
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2015-10-05
1000 Erschienen in
1000 Quellenangabe
  • 16:741
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2015
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12864-015-1904-7 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594904/ |
1000 Ergänzendes Material
  • https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-015-1904-7#Declarations |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: Downy mildews are the most speciose group of oomycetes and affect crops of great economic importance. So far, there is only a single deeply-sequenced downy mildew genome available, from Hyaloperonospora arabidopsidis. Further genomic resources for downy mildews are required to study their evolution, including pathogenicity effector proteins, such as RxLR effectors. Plasmopara halstedii is a devastating pathogen of sunflower and a potential pathosystem model to study downy mildews, as several Avr-genes and R-genes have been predicted and unlike Arabidopsis downy mildew, large quantities of almost contamination-free material can be obtained easily. RESULTS: Here a high-quality draft genome of Plasmopara halstedii is reported and analysed with respect to various aspects, including genome organisation, secondary metabolism, effector proteins and comparative genomics with other sequenced oomycetes. Interestingly, the present analyses revealed further variation of the RxLR motif, suggesting an important role of the conservation of the dEER-motif. Orthology analyses revealed the conservation of 28 RxLR-like core effectors among Phytophthora species. Only six putative RxLR-like effectors were shared by the two sequenced downy mildews, highlighting the fast and largely independent evolution of two of the three major downy mildew lineages. This is seemingly supported by phylogenomic results, in which downy mildews did not appear to be monophyletic. CONCLUSIONS: The genome resource will be useful for developing markers for monitoring the pathogen population and might provide the basis for new approaches to fight Phytophthora and downy mildew pathogens by targeting core pathogenicity effectors.
1000 Sacherschließung
lokal Oomycetes
lokal Microsatellites
lokal RxLR effectors
lokal Plant pathogen
lokal Comparative genomics
lokal Core effectors
lokal Obligate biotroph
lokal Phytohormones
lokal Evolution
lokal Downy mildew
lokal Promoters
1000 Fachgruppe
  1. Biologie |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. http://orcid.org/0000-0002-9660-6343|https://frl.publisso.de/adhoc/creator/WGlhLCBYaWFvanVhbg==|https://frl.publisso.de/adhoc/creator/Q2FubywgTGlsaWFuYSBNLg==|https://frl.publisso.de/adhoc/creator/RXZhbmdlbGlzdGksIEVkb3VhcmQ=|https://frl.publisso.de/adhoc/creator/S2VtZW4sIEVyaWM=|https://frl.publisso.de/adhoc/creator/SnVkZWxzb24sIEhvd2FyZA==|https://frl.publisso.de/adhoc/creator/T29tZSwgU3Rhbg==|https://frl.publisso.de/adhoc/creator/U2FtYmxlcywgQ2hyaXN0aW5l|https://frl.publisso.de/adhoc/creator/dmFuIGRlbiBIb29nZW4sIEQuIEpvaGFu|https://frl.publisso.de/adhoc/creator/S2l0bmVyLCBNaWxvc2xhdg==|https://frl.publisso.de/adhoc/creator/S2xlaW4sIEpvw6ts|https://frl.publisso.de/adhoc/creator/TWVpamVyLCBIYXJvbGQgSi4gRy4=|https://frl.publisso.de/adhoc/creator/U3ByaW5nLCBPdG1hcg==|https://frl.publisso.de/adhoc/creator/V2luLCBKb2U=|https://frl.publisso.de/adhoc/creator/WmlwcGVyLCBSZWluaGFyZA==|https://frl.publisso.de/adhoc/creator/Qm9kZSwgSGVsZ2UgQi4=|https://frl.publisso.de/adhoc/creator/R292ZXJzLCBGcmFuY2luZQ==|https://frl.publisso.de/adhoc/creator/S2Ftb3VuLCBTb3BoaWVu|https://frl.publisso.de/adhoc/creator/U2Nob3JuYWNrLCBTZWJhc3RpYW4=|https://frl.publisso.de/adhoc/creator/U3R1ZGhvbG1lLCBEYXZpZCBKLg==|https://frl.publisso.de/adhoc/creator/VmFuIGRlbiBBY2tlcnZla2VuLCBHdWlkbw==|https://frl.publisso.de/adhoc/creator/VGhpbmVzLCBNYXJjbw==
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  1. Hesse's State Ministry of Higher Education, Research and the Arts
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  1. LOEWE - Landes-Offensive zur Entwicklung Wissenschaftlich-ökonomischer Exzellenz
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