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1000 Titel
  • Indices of heart rate variability as potential early markers of metabolic stress and compromised regulatory capacity in dried-off high-yielding dairy cows
1000 Autor/in
  1. Erdmann, Sandra |
  2. Mohr, E. |
  3. Derno, Michael |
  4. Tuchscherer, Armin |
  5. Schäff, Christine T. |
  6. Börner, Sabrina |
  7. Kautzsch, Ulrike |
  8. Kuhla, Björn |
  9. Hammon, Harald |
  10. Röntgen, Monika |
1000 Erscheinungsjahr 2017
1000 LeibnizOpen
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2017-10-25
1000 Erschienen in
1000 Quellenangabe
  • 12(7): 1451-1461
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2017
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1017/S1751731117002725 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • High performing dairy cows experience distinct metabolic stress during periods of negative energy balance. Subclinical disorders of the cow’s energy metabolism facilitate failure of adaptational responses resulting in health problems and reduced performance. The autonomic nervous system (ANS) with its sympathetic and parasympathetic branches plays a predominant role in adaption to inadequate energy and/or fuel availability and mediation of the stress response. Therefore, we hypothesize that indices of heart rate variability (HRV) that reflect ANS activity and sympatho-vagal balance could be early markers of metabolic stress, and possibly useful to predict cows with compromised regulatory capacity. In this study we analysed the autonomic regulation and stress level of 10 pregnant dried-off German Holstein cows before, during and after a 10-h fasting period by using a wide range of HRV parameters. In addition heat production (HP), energy balance, feed intake, rumen fermentative activity, physical activity, non-esterified fatty acids, β-hydroxybutyric acid, cortisol and total ghrelin plasma concentrations, and body temperature (BT) were measured. In all cows fasting induced immediate regulatory adjustments including increased lipolysis (84%) and total ghrelin levels (179%), reduction of HP (−16%), standing time (−38%) and heart rate (−15%). However, by analysing frequency domain parameters of HRV (high-frequency (HF) and low-frequency (LF) components, ratio LF/HF) cows could be retrospectively assigned to groups reacting to food removal with increased or decreased activity of the parasympathetic branch of the ANS. Regression analysis reveals that under control conditions (feeding ad libitum) group differences were best predicted by the nonlinear domain HRV component Maxline (L MAX, R 2=0.76, threshold; TS=258). Compared with cows having L MAX values above TS (>L MAX: 348±17), those with L MAX values below TS (<L MAX: 109±26) had higher basal blood cortisol levels, lower concentrations of insulin, and respond to fasting with a shift of their sympatho-vagal balance towards a much stronger dominance of the sympathetic branch of the ANS and development of stress-induced hyperthermia. The data indicate a higher stress level, reduced well-being and restricted regulatory capacity in <L MAX cows. This assumption is in accord with the lower dry matter intake and energy corrected milk yield (16.0±0.7 and 42±2 kg/day) in lactating <L MAX compared with >L MAX cows (18.5±0.4 and 47.3 kg/day). From the present study, it seems conceivable that L MAX can be used as a predictive marker to discover alterations in central autonomic regulation that might precede metabolic disturbances.
1000 Sacherschließung
lokal stress
lokal autonomic nervous system
lokal dairy cow
lokal sympatho-vagal balance
lokal fasting
1000 Fachgruppe
  1. Agrarwissenschaften |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/RXJkbWFubiwgU2FuZHJh|https://frl.publisso.de/adhoc/creator/TW9ociwgRS4=|https://frl.publisso.de/adhoc/creator/RGVybm8sIE1pY2hhZWw=|https://frl.publisso.de/adhoc/creator/VHVjaHNjaGVyZXIsIEFybWlu|https://frl.publisso.de/adhoc/creator/U2Now6RmZiwgQ2hyaXN0aW5lIFQu|https://frl.publisso.de/adhoc/creator/QsO2cm5lciwgU2FicmluYQ==|https://frl.publisso.de/adhoc/creator/S2F1dHpzY2gsIFVscmlrZQ==|https://frl.publisso.de/adhoc/creator/S3VobGEsIEJqw7Zybg==|https://frl.publisso.de/adhoc/creator/SGFtbW9uLCBIYXJhbGQ=|https://frl.publisso.de/adhoc/creator/UsO2bnRnZW4sIE1vbmlrYQ==
1000 Förderer
  1. Deutsche Forschungsgemeinschaft (DFG) |
  2. Leibniz Institute for Farm Animal Biology (FBN) |
1000 Fördernummer
  1. SCHW 642/6-1, KU 1956/3-1; HA 4372/6-1
  2. -
1000 Förderprogramm
  1. -
  2. Open Access Fund
1000 Dateien
  1. Indices of heart rate variability as potential early markers of metabolic stress and compromised regulatory capacity in dried-off high-yielding dairy cows
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Deutsche Forschungsgemeinschaft (DFG) |
    1000 Förderprogramm -
    1000 Fördernummer SCHW 642/6-1, KU 1956/3-1; HA 4372/6-1
  2. 1000 joinedFunding-child
    1000 Förderer Leibniz Institute for Farm Animal Biology (FBN) |
    1000 Förderprogramm Open Access Fund
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6410212.rdf
1000 Erstellt am 2018-09-14T14:28:06.275+0200
1000 Erstellt von 122
1000 beschreibt frl:6410212
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Fri Sep 14 14:29:32 CEST 2018
1000 Objekt bearb. Fri Sep 14 14:29:14 CEST 2018
1000 Vgl. frl:6410212
1000 Oai Id
  1. oai:frl.publisso.de:frl:6410212 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

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