Download
fendo-09-00036.pdf 879,69KB
WeightNameValue
1000 Titel
  • Effects of Transport Duration and Environmental Conditions in Winter or Summer on the Concentrations of Insulin-Like Growth Factors and Insulin-Like Growth Factor-Binding Proteins in the Plasma of Market-Weight Pigs
1000 Autor/in
  1. Wirthgen, Elisa |
  2. Goumon, Sébastien |
  3. Kunze, Martin |
  4. Walz, Christina |
  5. Spitschak, Marion |
  6. Tuchscherer, Armin |
  7. Brown, Jennifer |
  8. Höflich, Christine |
  9. Faucitano, Luigi |
  10. Hoeflich, Andreas |
1000 Erscheinungsjahr 2018
1000 LeibnizOpen
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2018-02-13
1000 Erschienen in
1000 Quellenangabe
  • 9: 36
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2018
1000 Verlagsversion
  • https://doi.org/10.3389/fendo.2018.00036 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816936/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • In previous work using market-weight pigs, we had demonstrated that insulin-like growth factors (IGFs) and insulin-like growth factor binding proteins (IGFBPs) are regulated during shipment characterized by changing conditions of stress due to loading or unloading, transportation, lairage, and slaughter. In addition, we found in a previous study that IGFBP-2 concentrations were lower in pigs transported for longer periods of time. Therefore, we performed a more detailed study on the effects of transport duration and season on the plasma concentrations of IGFs and IGFBPs in adult pigs. For the study, exsanguination blood was collected from 240 market-weight barrows that were transported for 6, 12, or 18 h in January or July. IGF-I and -II were detected using commercial ELISAs whereas IGFBPs were quantified by quantitative Western ligand blotting. In addition, established markers of stress and metabolism were studied in the animals. The results show that plasma concentrations of IGFBP-3 were significantly reduced after 18 h of transport compared to shorter transport durations (6 and 12 h; p < 0.05). The concentrations of IGF-I in plasma were higher (p < 0.001) in pigs transported 12 h compared to shorter or longer durations. Season influenced plasma concentrations of IGFBP-3 and IGF-II (p < 0.05 and p < 0.01, respectively). Neither transport duration nor differential environmental conditions of winter or summer had an effect on glucocorticoids, albumin, triglycerides, or glucose concentrations (p > 0.05). However, low-density lipoprotein concentrations decreased after 18 h compared to 6 h of transport (p < 0.05), whereas high-density lipoprotein concentrations were higher (p < 0.05) in pigs transported for 12 or 18 h compared to those transported for only 6 h. Our findings indicate differential regulation of IGF-compounds in response to longer transport duration or seasonal changes and support current evidence of IGFs and IGFBPs as innovative animal-based indicators of psycho-social or metabolic stress in pigs.
1000 Sacherschließung
lokal animal welfare
lokal pig shipment
lokal insulin-like growth factor
lokal metabolism
lokal stress hormones
lokal biomarker
1000 Fachgruppe
  1. Biologie |
  2. Agrarwissenschaften |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/V2lydGhnZW4sIEVsaXNh|https://frl.publisso.de/adhoc/creator/R291bW9uLCBTw6liYXN0aWVu|https://frl.publisso.de/adhoc/creator/S3VuemUsIE1hcnRpbg==|https://frl.publisso.de/adhoc/creator/V2FseiwgQ2hyaXN0aW5h|https://frl.publisso.de/adhoc/creator/U3BpdHNjaGFrLCBNYXJpb24=|https://frl.publisso.de/adhoc/creator/VHVjaHNjaGVyZXIsIEFybWlu|https://frl.publisso.de/adhoc/creator/QnJvd24sIEplbm5pZmVy|https://frl.publisso.de/adhoc/creator/SMO2ZmxpY2gsIENocmlzdGluZQ==|https://frl.publisso.de/adhoc/creator/RmF1Y2l0YW5vLCBMdWlnaQ==|http://orcid.org/0000-0003-2018-2836
1000 Label
1000 Förderer
  1. Bundesministerium für Forschung und Technologie (BMBF) |
  2. Natural Sciences and Engineering Research Council of Canada |
  3. Alberta Pork |
  4. SaskPork |
  5. Manitoba Pork |
  6. Ontario Pork |
1000 Fördernummer
  1. 01HI1402
  2. -
  3. -
  4. -
  5. -
  6. -
1000 Förderprogramm
  1. Innovationsforum Tierwohl
  2. -
  3. -
  4. -
  5. -
  6. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Bundesministerium für Forschung und Technologie (BMBF) |
    1000 Förderprogramm Innovationsforum Tierwohl
    1000 Fördernummer 01HI1402
  2. 1000 joinedFunding-child
    1000 Förderer Natural Sciences and Engineering Research Council of Canada |
    1000 Förderprogramm -
    1000 Fördernummer -
  3. 1000 joinedFunding-child
    1000 Förderer Alberta Pork |
    1000 Förderprogramm -
    1000 Fördernummer -
  4. 1000 joinedFunding-child
    1000 Förderer SaskPork |
    1000 Förderprogramm -
    1000 Fördernummer -
  5. 1000 joinedFunding-child
    1000 Förderer Manitoba Pork |
    1000 Förderprogramm -
    1000 Fördernummer -
  6. 1000 joinedFunding-child
    1000 Förderer Ontario Pork |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6410752.rdf
1000 Erstellt am 2018-10-24T13:18:41.133+0200
1000 Erstellt von 122
1000 beschreibt frl:6410752
1000 Bearbeitet von 218
1000 Zuletzt bearbeitet Fri Jan 31 00:31:13 CET 2020
1000 Objekt bearb. Tue Dec 18 12:42:20 CET 2018
1000 Vgl. frl:6410752
1000 Oai Id
  1. oai:frl.publisso.de:frl:6410752 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

View source