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1000 Titel
  • The Relation between Polyphenols and Body Composition in US Hispanics/Latinos: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Study of Latinos Nutrition and Physical Activity Assessment Study (SOLNAS)
1000 Autor/in
  1. Makarem, Nour |
  2. Mossavar-Rahmani, Yasmin |
  3. Sotres-Alvarez, Daniela |
  4. Hua, Simin |
  5. Wong, William W |
  6. Van Horn, Linda |
  7. Daviglus, Martha L |
  8. Franke, Adrian A |
  9. Gellman, Marc D |
  10. Kaplan, Robert C |
  11. Beasley, Jeannette M |
1000 Erscheinungsjahr 2017
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2017-09-29
1000 Erschienen in
1000 Quellenangabe
  • 1(11):e001115
1000 Copyrightjahr
  • 2017
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.3945/cdn.117.001115 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998790/ |
1000 Ergänzendes Material
  • https://academic.oup.com/cdn/article/1/11/e001115/4735241#supplementary-data |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: Polyphenols offer high antioxidant potential that may protect against chronic diseases. Epidemiologic evidence documenting their influence on body composition and obesity risk is limited, particularly among Hispanics/Latinos who are disproportionately prone to obesity. OBJECTIVES: The aims of this study were to evaluate cross-sectional associations of urinary polyphenols with body mass index (BMI) and body fat percentage (%BF) in a diverse Hispanic/Latino population and to assess the reliability of polyphenol measurements. METHODS: Participants were 442 adults from the Study of Latinos/Nutrition and Physical Activity Assessment Study (SOLNAS) aged 18–74 y. Doubly labeled water was used as an objective recovery biomarker of energy. Polyphenol excretion from 24-h urine samples was assessed. Measures were repeated in a subsample (n = 90) to provide a reliability measure. Anthropometric measures were obtained by trained personnel, and %BF was measured by 18O dilution. Linear regression models were used to evaluate multivariable associations between body composition and polyphenols. Spearman correlation coefficients between BMI and %BF with polyphenols and intraclass correlation coefficients (ICCs) between polyphenol measures were computed. RESULTS: A weak correlation was observed for resveratrol and %BF (r = −0.11, P = 0.02). In multivariable-adjusted regression models, weak inverse associations were observed for resveratrol and urolithin A with %BF [β ± SE: −0.010 ± 0.004 (P = 0.007) and −0.004 ± 0.002 (P = 0.03), respectively]. For every 50% increase in these urinary polyphenols, there was a 1% and 0.4% decrease in %BF. Urolithin A was inversely associated with BMI (β ± SE: −0.004 ± 0.002; P = 0.02) and with 5% lower odds of obesity in models not adjusted for total energy expenditure (TEE; OR: 0.95; 95% CI: 0.91, 0.99; P = 0.02). For every 50% increase in urolithin A, there was a 0.4-unit decrease in BMI. Associations were attenuated after adjustment for TEE. Reliability study findings were indicative of weak to moderate correlations (ICCs: 0.11–0.65), representing a degree of within-person variation in polyphenol biomarkers. CONCLUSIONS: Although associations were weak, resveratrol and urolithin A were inversely associated with obesity. Repeated polyphenol urine measures could clarify their long-term impact on body adiposity.
1000 Sacherschließung
lokal body fat
lokal polyphenols
lokal doubly labeled water
lokal obesity
lokal Hispanic/Latino
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/TWFrYXJlbSwgTm91cg==|https://frl.publisso.de/adhoc/creator/TW9zc2F2YXItUmFobWFuaSwgWWFzbWlu|https://frl.publisso.de/adhoc/creator/U290cmVzLUFsdmFyZXosIERhbmllbGE=|https://frl.publisso.de/adhoc/creator/SHVhLCBTaW1pbg==|https://frl.publisso.de/adhoc/creator/V29uZywgV2lsbGlhbSBX|https://frl.publisso.de/adhoc/creator/VmFuIEhvcm4sIExpbmRh|https://frl.publisso.de/adhoc/creator/RGF2aWdsdXMsIE1hcnRoYSBM|https://frl.publisso.de/adhoc/creator/RnJhbmtlLCBBZHJpYW4gQQ==|https://frl.publisso.de/adhoc/creator/R2VsbG1hbiwgTWFyYyBE|https://frl.publisso.de/adhoc/creator/S2FwbGFuLCBSb2JlcnQgQw==|https://frl.publisso.de/adhoc/creator/QmVhc2xleSwgSmVhbm5ldHRlIE0=
1000 Label
1000 Förderer
  1. National Heart, Lung, and Blood Institute (NHLBI) |
  2. National Institute on Minority Health and Health Disparities |
  3. National Institute on Deafness and Other Communication Disorders |
  4. National Institute of Dental and Craniofacial Research |
  5. National Institute of Diabetes and Digestive and Kidney Diseases |
  6. National Institute of Neurological Disorders and Stroke |
  7. NIH–Office of Dietary Supplements |
  8. Sackler Institute |
  9. Feldstein Medical Foundation |
1000 Fördernummer
  1. R01HL095856; N01- HC65233; N01-HC65234; N01-HC65235; N01-HC65236; N01-HC65237
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1000 Förderprogramm
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1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer National Heart, Lung, and Blood Institute (NHLBI) |
    1000 Förderprogramm -
    1000 Fördernummer R01HL095856; N01- HC65233; N01-HC65234; N01-HC65235; N01-HC65236; N01-HC65237
  2. 1000 joinedFunding-child
    1000 Förderer National Institute on Minority Health and Health Disparities |
    1000 Förderprogramm -
    1000 Fördernummer -
  3. 1000 joinedFunding-child
    1000 Förderer National Institute on Deafness and Other Communication Disorders |
    1000 Förderprogramm -
    1000 Fördernummer -
  4. 1000 joinedFunding-child
    1000 Förderer National Institute of Dental and Craniofacial Research |
    1000 Förderprogramm -
    1000 Fördernummer -
  5. 1000 joinedFunding-child
    1000 Förderer National Institute of Diabetes and Digestive and Kidney Diseases |
    1000 Förderprogramm -
    1000 Fördernummer -
  6. 1000 joinedFunding-child
    1000 Förderer National Institute of Neurological Disorders and Stroke |
    1000 Förderprogramm -
    1000 Fördernummer -
  7. 1000 joinedFunding-child
    1000 Förderer NIH–Office of Dietary Supplements |
    1000 Förderprogramm -
    1000 Fördernummer -
  8. 1000 joinedFunding-child
    1000 Förderer Sackler Institute |
    1000 Förderprogramm -
    1000 Fördernummer -
  9. 1000 joinedFunding-child
    1000 Förderer Feldstein Medical Foundation |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6411996.rdf
1000 Erstellt am 2019-01-10T11:32:02.933+0100
1000 Erstellt von 218
1000 beschreibt frl:6411996
1000 Bearbeitet von 218
1000 Zuletzt bearbeitet 2019-11-07T11:24:22.726+0100
1000 Objekt bearb. Thu Nov 07 11:22:28 CET 2019
1000 Vgl. frl:6411996
1000 Oai Id
  1. oai:frl.publisso.de:frl:6411996 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
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