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1000 Titel
  • Consumption of Red Meat, but Not Cooking Oils High in Polyunsaturated Fat, Is Associated with Higher Arachidonic Acid Status in Singapore Chinese Adults
1000 Autor/in
  1. Seah, Jowy Yi Hoong |
  2. Gay, Gibson Ming Wei |
  3. Su, Jin |
  4. Tai, E-Shyong |
  5. Yuan, Jian-Min |
  6. Koh, Woon-Puay |
  7. Ong, Choon Nam |
  8. Van Dam, Rob M. |
1000 Erscheinungsjahr 2017
1000 Art der Datei
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2017-01-31
1000 Erschienen in
1000 Quellenangabe
  • 9(2):101
1000 Copyrightjahr
  • 2017
1000 Lizenz
1000 Verlagsversion
  • https://dx.doi.org/10.3390/nu9020101 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331532/ |
1000 Ergänzendes Material
  • https://www.mdpi.com/2072-6643/9/2/101#supplementary |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • High arachidonic acid (AA; 20:4 n − 6) status may have adverse effects on inflammation and risk of cardiovascular diseases. Concerns about high intake of n − 6 polyunsaturated fatty acids (PUFAs) are based on the premise that endogenous conversion from linoleic acid (LA; 18:2 n − 6) is an important source of AA, but few population-based studies have investigated dietary determinants of AA status. In this study, we examined habitual food consumption in relation to plasma concentrations of AA and other PUFAs in population-based studies. We used cross-sectional data from 269 healthy, ethnic Chinese participants (25–80 years old) with contrasting intakes of fish and red meat from the Singapore Prospective Study Program and 769 healthy participants (44–74 years old) from the Singapore Chinese Health Study as a validation set. Multivariable linear regression was used to examine PUFA intake (% energy) and food sources of PUFA (fish, red meat, poultry, soy and cooking oils) in relation to plasma PUFAs (AA, LA, dihomo-gamma-linolenic acid (DGLA; 20:3 n − 6), alpha-linolenic acid (ALA; 18:3 n − 3), eicosapentaenoic acid (EPA; 20:5 n − 3), and docosahexaenoic acid (DHA; 22:6 n − 3)) concentrations. Higher intake of red meat was associated with higher plasma AA concentrations. High intake of PUFA or PUFA-rich oils was associated with higher plasma ALA but not with plasma AA. Higher intakes of soy were associated with higher ALA and fish with higher DHA and EPA concentrations. These associations were statistically significant (p < 0.05) in both studies. Red meat consumption, but not PUFA or PUFA-rich cooking oil, was associated with circulating AA suggesting that intake of pre-formed AA rather than LA is an important determinant of AA status. A diet high in fish, soy products and polyunsaturated cooking oil, and low in red meat may be associated with an optimal plasma profile of PUFA in this Chinese population.
1000 Sacherschließung
lokal cardiovascular disease
lokal omega-3 fatty acid
lokal inflammation
lokal omega-6 fatty acid
lokal biomarkers
lokal polyunsaturated fatty acids
lokal diet
lokal plasma fatty acid
lokal cooking oil
1000 Fachgruppe
  1. Gesundheitswesen |
  2. Ernährungswissenschaften |
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/creator/U2VhaCwgSm93eSBZaSBIb29uZw==|https://frl.publisso.de/adhoc/creator/R2F5LCBHaWJzb24gTWluZyBXZWk=|https://frl.publisso.de/adhoc/creator/U3UsIEppbg==|https://frl.publisso.de/adhoc/creator/VGFpLCBFLVNoeW9uZw==|https://frl.publisso.de/adhoc/creator/WXVhbiwgSmlhbi1NaW4=|https://frl.publisso.de/adhoc/creator/S29oLCBXb29uLVB1YXk=|https://frl.publisso.de/adhoc/creator/T25nLCBDaG9vbiBOYW0=|https://frl.publisso.de/adhoc/creator/VmFuIERhbSwgUm9iIE0u
1000 Förderer
  1. National Institutes of Health (NIH)
  2. National Medical Research Council, Singapore
  3. Environmental and Occupational Health Research (CEOHR) National University of Singapore
  4. National Research Foundation (NRF) Singapore
  5. Prime Minister’s Office, Singapore
  6. Biomedical Research Council
1000 Fördernummer
  1. R01 CA144034; UM1 CA182876
  2. 0838/2004; 1270/2010
  3. -
  4. -
  5. -
  6. 03/1/27/18/216
1000 Förderprogramm
  1. -
  2. -
  3. Campus for Research Excellence and Technological Enterprise (CREATE)
  4. Campus for Research Excellence and Technological Enterprise (CREATE)
  5. Campus for Research Excellence and Technological Enterprise (CREATE)
  6. -
1000 Dateien
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6412583.rdf
1000 Erstellt am 2019-02-04T13:46:45.274+0100
1000 Erstellt von 122
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1000 Bearbeitet von 122
1000 Zuletzt bearbeitet 2019-02-04T13:47:41.052+0100
1000 Objekt bearb. Mon Feb 04 13:47:26 CET 2019
1000 Vgl. frl:6412583
1000 Oai Id
  1. oai:frl.publisso.de:frl:6412583 |
1000 Sichtbarkeit Metadaten public
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