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Langner-et-al_2019_Individual mortality information in the German Pharmacoepidemiological Research Database (GePaRD)_A validation study using a record linkage with a large cancer registry.pdf 349,79KB
WeightNameValue
1000 Titel
  • Individual mortality information in the German Pharmacoepidemiological Research Database (GePaRD): a validation study using a record linkage with a large cancer registry
1000 Autor/in
  1. Langner, Ingo |
  2. Ohlmeier, Christoph |
  3. Zeeb, Hajo |
  4. Haug, Ulrike |
  5. Riedel, Oliver |
1000 Erscheinungsjahr 2019
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2019-07-02
1000 Erschienen in
1000 Quellenangabe
  • 9(7):e02822
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2019
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1136/bmjopen-2018-028223 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • OBJECTIVE: Claims data need to be validated to assess their use for epidemiological research. This study aimed to examine the validity of mortality information in the German Pharmacoepidemiological Research Database (GePaRD). DESIGN: Validation study, secondary data, medical claims. SETTING: Claims data of two German nationwide acting statutory health insurance providers (SHIs) contributing data for GePaRD; record linkage with epidemiological cancer registry providing individual official mortality information. PARTICIPANTS: All women insured with the two SHIs whose insurance coverage ended in the period 2006–2013 and who were residents of North Rhine Westphalia. MEASURES: Descriptive statistics were used to analyse the performance of the linkage procedure. Further, we calculated measures of agreement between the official and the GePaRD-based vital status and assessed differences between the official and the GePaRD-based date of death. RESULTS: Of the 256 111 women of the linkage sample, 25 528 were classified as ‘deceased’ in GePaRD and the others as ‘alive’. Compared with the official data, the GePaRD-based vital status showed a sensitivity of 95.9% and a specificity of 99.4%. The negative predictive value was 99.6% and the positive predictive value 94.3%. The date of death agreed in 96.3% between both data sources. CONCLUSIONS: The vital status recorded in GePaRD was of high accuracy and discrepancies between dates of death in GePaRD and official dates were rare. This underlines the potential of the database for conducting large cohort studies with mortality as the endpoint.
1000 Sacherschließung
lokal Public health
lokal Epidemiology
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-8998-1236|https://frl.publisso.de/adhoc/uri/T2hsbWVpZXIsIENocmlzdG9waA==|https://orcid.org/0000-0001-7509-242X|https://orcid.org/0000-0002-1886-2923|https://frl.publisso.de/adhoc/uri/UmllZGVsLCBPbGl2ZXI=
1000 Label
1000 Förderer
  1. Bundesamt für Strahlenschutz |
  2. Bundesministerium für Umwelt, Naturschutz, Bau und Reaktorsicherheit |
  3. Bundesministerium für Gesundheit |
  4. Kooperationsgemeinschaft Mammographie |
  5. Leibniz-Gemeinschaft |
1000 Fördernummer
  1. UFOPLAN 3610S40002; 3614S40002
  2. UFOPLAN 3610S40002; 3614S40002
  3. UFOPLAN 3610S40002; 3614S40002
  4. UFOPLAN 3610S40002; 3614S40002
  5. -
1000 Förderprogramm
  1. -
  2. -
  3. -
  4. -
  5. Open Access Fund
1000 Dateien
  1. Individual mortality information in the German Pharmacoepidemiological Research Database (GePaRD)_A validation study using a record linkage with a large cancer registry
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Bundesamt für Strahlenschutz |
    1000 Förderprogramm -
    1000 Fördernummer UFOPLAN 3610S40002; 3614S40002
  2. 1000 joinedFunding-child
    1000 Förderer Bundesministerium für Umwelt, Naturschutz, Bau und Reaktorsicherheit |
    1000 Förderprogramm -
    1000 Fördernummer UFOPLAN 3610S40002; 3614S40002
  3. 1000 joinedFunding-child
    1000 Förderer Bundesministerium für Gesundheit |
    1000 Förderprogramm -
    1000 Fördernummer UFOPLAN 3610S40002; 3614S40002
  4. 1000 joinedFunding-child
    1000 Förderer Kooperationsgemeinschaft Mammographie |
    1000 Förderprogramm -
    1000 Fördernummer UFOPLAN 3610S40002; 3614S40002
  5. 1000 joinedFunding-child
    1000 Förderer Leibniz-Gemeinschaft |
    1000 Förderprogramm Open Access Fund
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6415253.rdf
1000 Erstellt am 2019-07-17T15:02:19.727+0200
1000 Erstellt von 266
1000 beschreibt frl:6415253
1000 Bearbeitet von 25
1000 Zuletzt bearbeitet Tue Jul 23 08:28:52 CEST 2019
1000 Objekt bearb. Tue Jul 23 08:28:51 CEST 2019
1000 Vgl. frl:6415253
1000 Oai Id
  1. oai:frl.publisso.de:frl:6415253 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

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