Download
Hebestreit_BIPS_31760215_Postprint.pdf 862,94KB
WeightNameValue
1000 Titel
  • Sex differences in the longitudinal associations between body composition and bone stiffness index in European children and adolescents
1000 Autor/in
  1. Cheng, Lan |
  2. Pohlabeln, Hermann |
  3. Ahrens, Wolfgang |
  4. Russo, Paola |
  5. Veidebaum, Toomas |
  6. Chadjigeorgiou, Charalambos |
  7. Molnár, Dénes |
  8. Eiben, Gabriele |
  9. De Henauw, Stefaan |
  10. Moreno, Luis A. |
  11. Page, Angie |
  12. Hebestreit, Antje |
1000 Mitwirkende/r
  1. The IDEFICS consortium |
  2. The I.Family consortium |
1000 Erscheinungsjahr 2019
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2019-11-21
1000 Erschienen in
1000 Quellenangabe
  • 131:115162
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2019
1000 Embargo
  • 2020-11-21
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1016/j.bone.2019.115162 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Fat mass (FM) and fat free mass (FFM) may influence bone health differentially. However, existing evidences on associations between FM, FFM and bone health are inconsistent and vary according to sex and maturity. The present study aims to evaluate longitudinal associations between FM, FFM and bone stiffness index (SI) among European children and adolescents with 6 years follow-up. A sample of 2468 children from the IDEFICS/I.Family was included, with repeated measurements of SI using calcaneal quantitative ultrasound, body composition using skinfold thickness, sedentary behaviors and physical activity using self-administrated questionnaires. Regression coefficients (β) and 99%-confidence intervals (99% CI) were calculated by sex-specified generalized linear mixed effects models to analyze the longitudinal associations between FM and FFM z-scores (zFM and zFFM) and SI percentiles, and to explore the possible interactions between zFM, zFFM and maturity. Baseline zFFM was observed to predict the change in SI percentiles in both boys (β = 4.57, 99% CI: 1.36, 7.78) and girls (β = 3.42, 99% CI: 0.05, 6.79) after 2 years. Moreover, baseline zFFM (β = 8.72, 99% CI: 3.18, 14.27 in boys and β = 5.89, 99% CI: 0.34, 11.44 in girls) and the change in zFFM (β = 6.58, 99% CI: 0.83, 12.34 in boys and β = 4.81, 99% CI: −0.41, 10.02 in girls) were positively associated with the change in SI percentiles after 6 years. In contrast, a negative association was observed between the change in zFM and SI percentiles in boys after 6 years (β = −3.70, 99% CI: −6.99, −0.42). Besides, an interaction was observed between the change in zFM and menarche on the change in SI percentiles in girls at 6 years follow-up (p = .009), suggesting a negative association before menarche while a positive association after menarche. Our findings support the existing evidences for a positive relationship between FFM and SI during growth. Furthermore, long-term FM gain was inversely associated with SI in boys, whereas opposing associations were observed across menarche in girls.
1000 Sacherschließung
lokal Pediatrics
lokal Body composition
lokal Sex differences
lokal Bone stiffness index
lokal Longitudinal study
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/Q2hlbmcsIExhbg==|https://orcid.org/0000-0002-9575-1119|https://orcid.org/0000-0003-3777-570X|https://frl.publisso.de/adhoc/uri/UnVzc28sIFBhb2xh|https://frl.publisso.de/adhoc/uri/VmVpZGViYXVtLCBUb29tYXM=|https://frl.publisso.de/adhoc/uri/Q2hhZGppZ2Vvcmdpb3UsIENoYXJhbGFtYm9z|https://frl.publisso.de/adhoc/uri/TW9sbsOhciwgRMOpbmVz|https://frl.publisso.de/adhoc/uri/RWliZW4sIEdhYnJpZWxl|https://frl.publisso.de/adhoc/uri/RGUgSGVuYXV3LCBTdGVmYWFu|https://frl.publisso.de/adhoc/uri/TW9yZW5vLCBMdWlzIEEu|https://frl.publisso.de/adhoc/uri/UGFnZSwgQW5naWU=|https://orcid.org/0000-0001-7354-5958|https://frl.publisso.de/adhoc/uri/VGhlIElERUZJQ1MgY29uc29ydGl1bQ==|https://frl.publisso.de/adhoc/uri/VGhlIEkuRmFtaWx5IGNvbnNvcnRpdW0=
1000 Label
1000 Förderer
  1. China Scholarship Council |
  2. Sixth Framework Programme |
  3. Seventh Framework Programme |
1000 Fördernummer
  1. -
  2. 016181
  3. 266044
1000 Förderprogramm
  1. -
  2. FOOD
  3. -
1000 Dateien
  1. Nutzungsvereinbarung
  2. Elsevier_self-archiving policy
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer China Scholarship Council |
    1000 Förderprogramm -
    1000 Fördernummer -
  2. 1000 joinedFunding-child
    1000 Förderer Sixth Framework Programme |
    1000 Förderprogramm FOOD
    1000 Fördernummer 016181
  3. 1000 joinedFunding-child
    1000 Förderer Seventh Framework Programme |
    1000 Förderprogramm -
    1000 Fördernummer 266044
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6421455.rdf
1000 Erstellt am 2020-06-22T11:24:41.196+0200
1000 Erstellt von 266
1000 beschreibt frl:6421455
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Mon Nov 30 10:48:32 CET 2020
1000 Objekt bearb. Mon Nov 30 10:48:31 CET 2020
1000 Vgl. frl:6421455
1000 Oai Id
  1. oai:frl.publisso.de:frl:6421455 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

View source