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1000 Titel
  • Metabolic status in children and its transitions during childhood and adolescence—the IDEFICS/I.Family study
1000 Autor/in
  1. Börnhorst, Claudia |
  2. Russo, Paola |
  3. Veidebaum, Toomas |
  4. Tornaritis, Michael |
  5. Molnár, Dénes |
  6. Lissner, Lauren |
  7. Mårild, Staffan |
  8. De Henauw, Stefaan |
  9. Moreno, Luis A. |
  10. Intemann, Timm |
  11. Wolters, Maike |
  12. Ahrens, Wolfgang |
  13. Floegel, Anna |
1000 Mitwirkende/r
  1. The IDEFICS consortium |
  2. The I.Family consortium |
1000 Erscheinungsjahr 2019
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2019-05-16
1000 Erschienen in
1000 Quellenangabe
  • 48(5):1673-1683
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2019
1000 Embargo
  • 2020-05-16
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1093/ije/dyz097 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: This study aimed to investigate metabolic status in children and its transitions into adolescence. METHODS: The analysis was based on 6768 children who participated in the European IDEFICS/I.Family cohort (T0 2007/2008, T1 2009/2010 and/or T3 2013/2014; mean ages: 6.6, 8.4 and 12.0 years, respectively) and provided at least two measurements of waist circumference, blood pressure, blood glucose and lipids over time. Latent transition analysis was used to identify groups with similar metabolic status and to estimate transition probabilities. RESULTS: The best-fitting model identified five latent groups: (i) metabolically healthy (61.5%; probability for group membership at T0); (ii) abdominal obesity (15.9%); (iii) hypertension (7.0%); (iv) dyslipidaemia (9.0%); and (v) several metabolic syndrome (MetS) components (6.6%). The probability of metabolically healthy children at T0 remaining healthy at T1 was 86.6%; when transitioning from T1 to T3, it was 90.1%. Metabolically healthy children further had a 6.7% probability of developing abdominal obesity at T1. Children with abdominal obesity at T0 had an 18.5% probability of developing several metabolic syndrome (MetS) components at T1. The subgroup with dyslipidaemia at T0 had the highest chances of becoming metabolically healthy at T1 (32.4%) or at T3 (35.1%). Only a minor proportion of children showing several MetS components at T0 were classified as healthy at follow-up; 99.8% and 88.3% remained in the group with several disorders at T1 and T3, respectively. CONCLUSIONS: Our study identified five distinct metabolic statuses in children and adolescents. Although lipid disturbances seem to be quite reversible, abdominal obesity is likely to be followed by further metabolic disturbances.
1000 Sacherschließung
lokal Metabolic syndrome
lokal I.Family
lokal Waist circumference
lokal Glucose disturbances
lokal IDEFICS
lokal Latent transition analysis
lokal Dyslipidaemia
lokal Hypertension
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-9004-1540|https://frl.publisso.de/adhoc/uri/UnVzc28sIFBhb2xh|https://frl.publisso.de/adhoc/uri/VmVpZGViYXVtLCBUb29tYXM=|https://frl.publisso.de/adhoc/uri/VG9ybmFyaXRpcywgTWljaGFlbA==|https://frl.publisso.de/adhoc/uri/TW9sbsOhciwgRMOpbmVz|https://frl.publisso.de/adhoc/uri/TGlzc25lciwgTGF1cmVu|https://frl.publisso.de/adhoc/uri/TcOlcmlsZCwgU3RhZmZhbg==|https://frl.publisso.de/adhoc/uri/RGUgSGVuYXV3LCBTdGVmYWFu|https://frl.publisso.de/adhoc/uri/TW9yZW5vLCBMdWlzIEEu|https://orcid.org/0000-0001-7836-3643|https://orcid.org/0000-0002-4943-2141|https://orcid.org/0000-0003-3777-570X|https://frl.publisso.de/adhoc/uri/RmxvZWdlbCwgQW5uYQ==|https://frl.publisso.de/adhoc/uri/VGhlIElERUZJQ1MgY29uc29ydGl1bQ==|https://frl.publisso.de/adhoc/uri/VGhlIEkuRmFtaWx5IGNvbnNvcnRpdW0=
1000 Label
1000 Förderer
  1. Sixth Framework Programme |
  2. Seventh Framework Programme |
1000 Fördernummer
  1. 016181 (FOOD)
  2. 266044
1000 Förderprogramm
  1. -
  2. -
1000 Dateien
  1. Nutzungsvereinbarung
  2. Oxford_self-archiving-policy
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Sixth Framework Programme |
    1000 Förderprogramm -
    1000 Fördernummer 016181 (FOOD)
  2. 1000 joinedFunding-child
    1000 Förderer Seventh Framework Programme |
    1000 Förderprogramm -
    1000 Fördernummer 266044
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6421458.rdf
1000 Erstellt am 2020-06-22T13:46:03.869+0200
1000 Erstellt von 266
1000 beschreibt frl:6421458
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Tue Jul 14 06:46:34 CEST 2020
1000 Objekt bearb. Tue Jul 14 06:46:33 CEST 2020
1000 Vgl. frl:6421458
1000 Oai Id
  1. oai:frl.publisso.de:frl:6421458 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

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