Sociodemographic, clinical and laboratory factors on admission associated with COVID-19 mortality in hospitalized patients: A retrospective observational study

  1. Rivera-Izquierdo, Mario ORCID logo
  2. del Carmen Valero-Ubierna, María
  3. R-delAmo, Juan Luis
  4. Fernández-García, Miguel Ángel
  5. Martínez-Diz, Silvia
  6. Tahery-Mahmoud, Arezu
  7. Rodríguez-Camacho, Marta
  8. Gámiz-Molina, Ana Belén
  9. Barba-Gyengo, Nicolás
  10. Gámez-Baeza, Pablo
  11. Cabrero-Rodríguez, Celia
  12. Guirado-Ruiz, Pedro Antonio
  13. Martín-Romero, Divina Tatiana
  14. Láinez-Ramos-Bossini, Antonio Jesús
  15. Sánchez-Pérez, María Rosa
  16. Mancera-Romero, José
  17. García-Martín, Miguel
  18. Martín-delosReyes, Luis Miguel ORCID logo
  19. Martínez-Ruiz, Virginia
  20. Lardelli-Claret, Pablo
  21. Jiménez-Mejías, Eladio

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WeightNameValue
1000 Titel
  • Sociodemographic, clinical and laboratory factors on admission associated with COVID-19 mortality in hospitalized patients: A retrospective observational study
1000 Autor/in
  1. Rivera-Izquierdo, Mario |
  2. del Carmen Valero-Ubierna, María |
  3. R-delAmo, Juan Luis |
  4. Fernández-García, Miguel Ángel |
  5. Martínez-Diz, Silvia |
  6. Tahery-Mahmoud, Arezu |
  7. Rodríguez-Camacho, Marta |
  8. Gámiz-Molina, Ana Belén |
  9. Barba-Gyengo, Nicolás |
  10. Gámez-Baeza, Pablo |
  11. Cabrero-Rodríguez, Celia |
  12. Guirado-Ruiz, Pedro Antonio |
  13. Martín-Romero, Divina Tatiana |
  14. Láinez-Ramos-Bossini, Antonio Jesús |
  15. Sánchez-Pérez, María Rosa |
  16. Mancera-Romero, José |
  17. García-Martín, Miguel |
  18. Martín-delosReyes, Luis Miguel |
  19. Martínez-Ruiz, Virginia |
  20. Lardelli-Claret, Pablo |
  21. Jiménez-Mejías, Eladio |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-06-25
1000 Erschienen in
1000 Quellenangabe
  • 15(6):e0235107
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1371/journal.pone.0235107 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: To identify and quantify associations between baseline characteristics on hospital admission and mortality in patients with COVID-19 at a tertiary hospital in Spain. METHODS AND FINDINGS: This retrospective case series included 238 patients hospitalized for COVID-19 at Hospital Universitario Clínico San Cecilio (Granada, Spain) who were discharged or who died. Electronic medical records were reviewed to obtain information on sex, age, personal antecedents, clinical features, findings on physical examination, and laboratory results for each patient. Associations between mortality and baseline characteristics were estimated as hazard ratios (HR) calculated with Cox regression models. Series mortality was 25.6%. Among patients with dependence for basic activities of daily living, 78.7% died, and among patients residing in retirement homes, 80.8% died. The variables most clearly associated with a greater hazard of death were age (3% HR increase per 1-year increase in age; 95%CI 1–6), diabetes mellitus (HR 2.42, 95%CI 1.43–4.09), SatO2/FiO2 ratio (43% HR reduction per 1-point increase; 95%CI 23–57), SOFA score (19% HR increase per 1-point increase, 95%CI 5–34) and CURB-65 score (76% HR increase per 1-point increase, 95%CI 23–143). CONCLUSIONS: The patients residing in retirement homes showed great vulnerability. The main baseline factors that were independently associated with mortality in patients hospitalized for COVID-19 were older age, diabetes mellitus, low SatO2/FiO2 ratio, and high SOFA and CURB-65 scores.
1000 Sacherschließung
lokal Dyspnea
gnd 1206347392 COVID-19
lokal Hospitals
lokal Fevers
lokal Diabetes mellitus
lokal Cardiovascular diseases
lokal Coughing
lokal Spain
lokal Death rates
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-6159-6037|https://frl.publisso.de/adhoc/uri/ZGVsIENhcm1lbiBWYWxlcm8tVWJpZXJuYSwgTWFyw61h|https://frl.publisso.de/adhoc/uri/Ui1kZWxBbW8sIEp1YW4gTHVpcw==|https://frl.publisso.de/adhoc/uri/RmVybsOhbmRlei1HYXJjw61hLCBNaWd1ZWwgw4FuZ2Vs|https://frl.publisso.de/adhoc/uri/TWFydMOtbmV6LURpeiwgU2lsdmlh|https://frl.publisso.de/adhoc/uri/VGFoZXJ5LU1haG1vdWQsIEFyZXp1|https://frl.publisso.de/adhoc/uri/Um9kcsOtZ3Vlei1DYW1hY2hvLCBNYXJ0YQ==|https://frl.publisso.de/adhoc/uri/R8OhbWl6LU1vbGluYSwgQW5hIEJlbMOpbg==|https://frl.publisso.de/adhoc/uri/QmFyYmEtR3llbmdvLCBOaWNvbMOhcw==|https://frl.publisso.de/adhoc/uri/R8OhbWV6LUJhZXphLCBQYWJsbw==|https://frl.publisso.de/adhoc/uri/Q2FicmVyby1Sb2Ryw61ndWV6LCBDZWxpYQ==|https://frl.publisso.de/adhoc/uri/R3VpcmFkby1SdWl6LCBQZWRybyBBbnRvbmlv|https://frl.publisso.de/adhoc/uri/TWFydMOtbi1Sb21lcm8sIERpdmluYSBUYXRpYW5h|https://frl.publisso.de/adhoc/uri/TMOhaW5lei1SYW1vcy1Cb3NzaW5pLCBBbnRvbmlvIEplc8O6cw==|https://frl.publisso.de/adhoc/uri/U8OhbmNoZXotUMOpcmV6LCBNYXLDrWEgUm9zYQ==|https://frl.publisso.de/adhoc/uri/TWFuY2VyYS1Sb21lcm8sIEpvc8Op|https://frl.publisso.de/adhoc/uri/R2FyY8OtYS1NYXJ0w61uLCBNaWd1ZWw=|https://orcid.org/0000-0002-2163-354X|https://frl.publisso.de/adhoc/uri/TWFydMOtbmV6LVJ1aXosIFZpcmdpbmlh|https://frl.publisso.de/adhoc/uri/TGFyZGVsbGktQ2xhcmV0LCBQYWJsbw==|https://frl.publisso.de/adhoc/uri/Smltw6luZXotTWVqw61hcywgRWxhZGlv
1000 Label
1000 Förderer
  1. SEMERGEN-UGR |
  2. Universidad de Granada |
1000 Fördernummer
  1. -
  2. -
1000 Förderprogramm
  1. Cátedra de Docencia e Investigación en Medicina de Familia
  2. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer SEMERGEN-UGR |
    1000 Förderprogramm Cátedra de Docencia e Investigación en Medicina de Familia
    1000 Fördernummer -
  2. 1000 joinedFunding-child
    1000 Förderer Universidad de Granada |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6421549.rdf
1000 Erstellt am 2020-06-29T14:43:55.818+0200
1000 Erstellt von 122
1000 beschreibt frl:6421549
1000 Bearbeitet von 122
1000 Zuletzt bearbeitet Mon Jun 29 14:45:19 CEST 2020
1000 Objekt bearb. Mon Jun 29 14:44:54 CEST 2020
1000 Vgl. frl:6421549
1000 Oai Id
  1. oai:frl.publisso.de:frl:6421549 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
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