Download
pone.0239443.pdf 606,31KB
WeightNameValue
1000 Titel
  • Ischemic stroke in COVID-19: An urgent need for early identification and management
1000 Autor/in
  1. Jillella, Dinesh |
  2. Janocko, Nicholas J. |
  3. Nahab, Fadi |
  4. Benameur, Karima |
  5. Greene, James G. |
  6. Wright, Wendy L. |
  7. Obideen, Mahmoud |
  8. Rangaraju, Srikant |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-09-18
1000 Erschienen in
1000 Quellenangabe
  • 15(9):e0239443
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1371/journal.pone.0239443 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500690/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • OBJECTIVE: In the setting of the Coronavirus Disease 2019 (COVID-19) global pandemic caused by SARS-CoV-2, a potential association of this disease with stroke has been suggested. We aimed to describe the characteristics of patients who were admitted with COVID-19 and had an acute ischemic stroke (AIS). METHODS: This is a case series of PCR-confirmed COVID-19 patients with ischemic stroke admitted to an academic health system in metropolitan Atlanta, Georgia (USA) between March 24th, 2020 and July 17th, 2020. Demographic, clinical, and radiographic characteristics were described. RESULTS: Of 396 ischemic stroke patients admitted during this study period, 13 (2.5%) were also diagnosed with COVID-19. The mean age of patients was 61.6 ± 10.8 years, 10 (76.9%) male, 8 (61.5%) were Black Americans, mean time from last normal was 4.97 ± 5.1 days, and only one received acute reperfusion therapy. All 13 patients had at least one stroke-associated co-morbidity. The predominant pattern of ischemic stroke was embolic with 4 explained by atrial fibrillation. COVID-19 patients had a significantly higher rate of cryptogenic stroke than non-COVID-19 patients during the study period (69% vs 17%, p = 0.0001). CONCLUSIONS: In our case series, ischemic stroke affected COVID-19 patients with traditional stroke risk factors at an age typically seen in non-COVID populations, and mainly affecting males and Black Americans. We observed a predominantly embolic pattern of stroke with a higher than expected rate of cryptogenic strokes, a prolonged median time to presentation and symptom recognition limiting the use of acute reperfusion treatments. These results highlight the need for increased community awareness, early identification, and management of AIS in COVID-19 patients.
1000 Sacherschließung
lokal Stroke
gnd 1206347392 COVID-19
lokal Cardiovascular disease risk
lokal Magnetic resonance imaging
lokal Atrial fibrillation
lokal Head
lokal Infarction
lokal Ischemic stroke
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-5399-0170|https://frl.publisso.de/adhoc/uri/SmFub2NrbywgTmljaG9sYXMgSi4=|https://frl.publisso.de/adhoc/uri/TmFoYWIsIEZhZGk=|https://orcid.org/0000-0002-4599-5705|https://frl.publisso.de/adhoc/uri/R3JlZW5lLCBKYW1lcyBHLg==|https://frl.publisso.de/adhoc/uri/V3JpZ2h0LCBXZW5keSBMLg==|https://frl.publisso.de/adhoc/uri/T2JpZGVlbiwgTWFobW91ZA==|https://frl.publisso.de/adhoc/uri/UmFuZ2FyYWp1LCBTcmlrYW50
1000 Label
1000 Fördernummer
  1. -
1000 Förderprogramm
  1. -
1000 Dateien
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6426789.rdf
1000 Erstellt am 2021-04-14T11:30:37.667+0200
1000 Erstellt von 5
1000 beschreibt frl:6426789
1000 Bearbeitet von 25
1000 Zuletzt bearbeitet Thu May 06 13:09:18 CEST 2021
1000 Objekt bearb. Thu May 06 13:08:52 CEST 2021
1000 Vgl. frl:6426789
1000 Oai Id
  1. oai:frl.publisso.de:frl:6426789 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

View source