The changes of the peripheral CD4+ lymphocytes and inflammatory cytokines in Patients with COVID-19

  1. Sun, Hua-Bao
  2. Zhang, Yi-Ming
  3. Huang, Li-Gui
  4. Lai, Qi-Nan
  5. Mo, Qun
  6. Ye, Xin-Zhou
  7. Wang, Tao
  8. Zhu, Zhong-Zhen
  9. Lv, Xiao-Lin
  10. Luo, Yan-Ji
  11. Gao, Shi-Ding
  12. Xu, Jin-Song
  13. Zhu, Hao-Hao
  14. Li, Ting
  15. wang, zhanke ORCID logo

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WeightNameValue
1000 Titel
  • The changes of the peripheral CD4+ lymphocytes and inflammatory cytokines in Patients with COVID-19
1000 Autor/in
  1. Sun, Hua-Bao |
  2. Zhang, Yi-Ming |
  3. Huang, Li-Gui |
  4. Lai, Qi-Nan |
  5. Mo, Qun |
  6. Ye, Xin-Zhou |
  7. Wang, Tao |
  8. Zhu, Zhong-Zhen |
  9. Lv, Xiao-Lin |
  10. Luo, Yan-Ji |
  11. Gao, Shi-Ding |
  12. Xu, Jin-Song |
  13. Zhu, Hao-Hao |
  14. Li, Ting |
  15. wang, zhanke |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-09-25
1000 Erschienen in
1000 Quellenangabe
  • 15(9):e0239532
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1371/journal.pone.0239532 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518571/ |
1000 Ergänzendes Material
  • https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0239532#sec016 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • To investigate the clinical value of changes in the subtypes of peripheral blood lymphocytes and levels of inflammatory cytokines in patients with COVID-19, the total numbers of lymphocytes and CD4+ lymphocytes and the ratio of CD4+/CD8+ lymphocytes were calculated and observed in different groups of patients with COVID-19. The results show that the lymphocytopenia in patients with COVID-19 was mainly manifested by decreases in the CD4+ T lymphocyte number and the CD4+/CD8+ ratio. The decreased number of CD4+ T lymphocytes and the elevated levels of TNF-α and IL-6 were correlated with the severity of COVID-19 disease.
1000 Sacherschließung
lokal Cytokines
lokal Blood
gnd 1206347392 COVID-19
lokal Blood plasma
lokal Lymphocytes
lokal Virus testing
lokal T cells
lokal Blood cells
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/U3VuLCBIdWEtQmFv|https://frl.publisso.de/adhoc/uri/WmhhbmcsIFlpLU1pbmc=|https://frl.publisso.de/adhoc/uri/SHVhbmcsIExpLUd1aQ==|https://frl.publisso.de/adhoc/uri/TGFpLCBRaS1OYW4=|https://frl.publisso.de/adhoc/uri/TW8sIFF1bg==|https://frl.publisso.de/adhoc/uri/WWUsIFhpbi1aaG91|https://frl.publisso.de/adhoc/uri/V2FuZywgVGFv|https://frl.publisso.de/adhoc/uri/IFpodSwgWmhvbmctWmhlbg==|https://frl.publisso.de/adhoc/uri/IEx2LCBYaWFvLUxpbg==|https://frl.publisso.de/adhoc/uri/THVvLCBZYW4tSmk=|https://frl.publisso.de/adhoc/uri/R2FvLCBTaGktRGluZw==|https://frl.publisso.de/adhoc/uri/WHUsIEppbi1Tb25n|https://frl.publisso.de/adhoc/uri/Wmh1LCBIYW8tSGFv|https://frl.publisso.de/adhoc/uri/TGksIFRpbmc=|https://orcid.org/0000-0001-6473-4968
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1000 Erstellt am 2021-04-21T06:39:09.582+0200
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1000 Zuletzt bearbeitet 2021-05-06T12:59:57.903+0200
1000 Objekt bearb. Thu May 06 12:59:48 CEST 2021
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