Specific Susceptibility to COVID-19 in Adults with Down Syndrome

  1. Illouz, Tomer
  2. Biragyn, Arya
  3. Frenkel-Morgenstern, Milana
  4. Weissberg, Orly
  5. Gorohovski, Alessandro
  6. Merzon, Eugene
  7. Green, Ilan
  8. Iulita, Florencia
  9. Flores-Aguilar, Lisi
  10. Dierssen, Mara
  11. De Toma, Ilario
  12. Lifshitz, Hefziba
  13. Antonarakis, Stylianos E.
  14. Yu, Eugene
  15. Herault, Yann
  16. Potier, Marie-Claude
  17. Botté, Alexandra
  18. Roper, Randall
  19. Sredni, Benjamin
  20. Sarid, Ronit
  21. London, Jacqueline
  22. Mobley, William
  23. Strydom, Andre
  24. okun, eitan ORCID logo

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WeightNameValue
1000 Titel
  • Specific Susceptibility to COVID-19 in Adults with Down Syndrome
1000 Autor/in
  1. Illouz, Tomer |
  2. Biragyn, Arya |
  3. Frenkel-Morgenstern, Milana |
  4. Weissberg, Orly |
  5. Gorohovski, Alessandro |
  6. Merzon, Eugene |
  7. Green, Ilan |
  8. Iulita, Florencia |
  9. Flores-Aguilar, Lisi |
  10. Dierssen, Mara |
  11. De Toma, Ilario |
  12. Lifshitz, Hefziba |
  13. Antonarakis, Stylianos E. |
  14. Yu, Eugene |
  15. Herault, Yann |
  16. Potier, Marie-Claude |
  17. Botté, Alexandra |
  18. Roper, Randall |
  19. Sredni, Benjamin |
  20. Sarid, Ronit |
  21. London, Jacqueline |
  22. Mobley, William |
  23. Strydom, Andre |
  24. okun, eitan |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-03-04
1000 Erschienen in
1000 Quellenangabe
  • Ahead of print
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s12017-021-08651-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929736/ |
1000 Ergänzendes Material
  • https://link.springer.com/article/10.1007/s12017-021-08651-5#Sec12 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • The current SARS-CoV-2 outbreak, which causes COVID-19, is particularly devastating for individuals with chronic medical conditions, in particular those with Down Syndrome (DS) who often exhibit a higher prevalence of respiratory tract infections, immune dysregulation and potential complications. The incidence of Alzheimer’s disease (AD) is much higher in DS than in the general population, possibly increasing further the risk of COVID-19 infection and its complications. Here we provide a biological overview with regard to specific susceptibility of individuals with DS to SARS-CoV-2 infection as well as data from a recent survey on the prevalence of COVID-19 among them. We see an urgent need to protect people with DS, especially those with AD, from COVID-19 and future pandemics and focus on developing protective measures, which also include interventions by health systems worldwide for reducing the negative social effects of long-term isolation and increased periods of hospitalization.
1000 Sacherschließung
gnd 1206347392 COVID-19
lokal Down syndrome
lokal Vaccine
lokal Immune dysregulation
lokal SARS-CoV-2
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
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1000 Label
1000 Förderer
  1. National Institute on Aging |
1000 Fördernummer
  1. -
1000 Förderprogramm
  1. Intramural Research Program
1000 Dateien
  1. Specific Susceptibility to COVID-19 in Adults with Down Syndrome
    Specific Susceptibility to COVID-19 in Adults with Down Syndrome
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer National Institute on Aging |
    1000 Förderprogramm Intramural Research Program
    1000 Fördernummer -
1000 Objektart article
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1000 @id frl:6427472.rdf
1000 Erstellt am 2021-05-14T07:42:54.602+0200
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1000 Bearbeitet von 317
1000 Zuletzt bearbeitet 2021-11-09T08:37:03.419+0100
1000 Objekt bearb. Tue Nov 09 08:36:34 CET 2021
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