The giant diploid faba genome unlocks variation in a global protein crop

  1. Jayakodi, Murukarthick ORCID logo
  2. Golicz, Agnieszka ORCID logo
  3. Kreplak, Jonathan
  4. Fechete, Lavinia Ioana ORCID logo
  5. Angra, Deepti
  6. Bednar, Petr ORCID logo
  7. bornhofen, elesandro ORCID logo
  8. Zhang, Hailin ORCID logo
  9. Boussageon, Raphael ORCID logo
  10. Kaur, Sukhjiwan ORCID logo
  11. Cheung, Kwok ORCID logo
  12. Cizkova, Jana ORCID logo
  13. Gundlach, Heidrun ORCID logo
  14. Hallab, Asis
  15. Imbert, Baptiste ORCID logo
  16. Keeble-Gagnère, Gabriel
  17. Koblížková, Andrea
  18. Kobrlová, Lucie ORCID logo
  19. Krejčí, Petra ORCID logo
  20. Wisén Mouritzen, Troels ORCID logo
  21. Neumann, Pavel ORCID logo
  22. Nadzieja, Marcin ORCID logo
  23. Nielsen, Linda Kærgaard ORCID logo
  24. Novak, Petr ORCID logo
  25. Orabi, Jihad
  26. Padmarasu, Sudharsan ORCID logo
  27. Robertson-Shersby-Harvie, Tom
  28. Robledillo, Laura Ávila
  29. Schiemann, Andrea
  30. Tanskanen, Jaakko
  31. Törönen, Petri
  32. Warsame, Ahmed ORCID logo
  33. Wittenberg, Alexander H. J. ORCID logo
  34. Himmelbach, Axel ORCID logo
  35. AUBERT, Gregoire ORCID logo
  36. Courty, Pierre-Emmanuel
  37. Dolezel, Jaroslav ORCID logo
  38. holm, liisa ORCID logo
  39. Janss, Luc ORCID logo
  40. Khazaei, Hamid ORCID logo
  41. Macas, Jiri ORCID logo
  42. Mascher, Martin ORCID logo
  43. Smykal, Petr ORCID logo
  44. Snowdon, Rod ORCID logo
  45. Stein, Nils ORCID logo
  46. Stoddard, Fred ORCID logo
  47. Stougaard, Jens
  48. Tayeh, Nadim
  49. Torres, Ana M. ORCID logo
  50. Usadel, Björn ORCID logo
  51. Schubert, Ingo ORCID logo
  52. O'Sullivan, Donal ORCID logo
  53. Schulman, Alan ORCID logo
  54. Andersen, Stig U. ORCID logo

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1000 Titel
  • The giant diploid faba genome unlocks variation in a global protein crop
1000 Autor/in
  1. Jayakodi, Murukarthick |
  2. Golicz, Agnieszka |
  3. Kreplak, Jonathan |
  4. Fechete, Lavinia Ioana |
  5. Angra, Deepti |
  6. Bednar, Petr |
  7. bornhofen, elesandro |
  8. Zhang, Hailin |
  9. Boussageon, Raphael |
  10. Kaur, Sukhjiwan |
  11. Cheung, Kwok |
  12. Cizkova, Jana |
  13. Gundlach, Heidrun |
  14. Hallab, Asis |
  15. Imbert, Baptiste |
  16. Keeble-Gagnère, Gabriel |
  17. Koblížková, Andrea |
  18. Kobrlová, Lucie |
  19. Krejčí, Petra |
  20. Wisén Mouritzen, Troels |
  21. Neumann, Pavel |
  22. Nadzieja, Marcin |
  23. Nielsen, Linda Kærgaard |
  24. Novak, Petr |
  25. Orabi, Jihad |
  26. Padmarasu, Sudharsan |
  27. Robertson-Shersby-Harvie, Tom |
  28. Robledillo, Laura Ávila |
  29. Schiemann, Andrea |
  30. Tanskanen, Jaakko |
  31. Törönen, Petri |
  32. Warsame, Ahmed |
  33. Wittenberg, Alexander H. J. |
  34. Himmelbach, Axel |
  35. AUBERT, Gregoire |
  36. Courty, Pierre-Emmanuel |
  37. Dolezel, Jaroslav |
  38. holm, liisa |
  39. Janss, Luc |
  40. Khazaei, Hamid |
  41. Macas, Jiri |
  42. Mascher, Martin |
  43. Smykal, Petr |
  44. Snowdon, Rod |
  45. Stein, Nils |
  46. Stoddard, Fred |
  47. Stougaard, Jens |
  48. Tayeh, Nadim |
  49. Torres, Ana M. |
  50. Usadel, Björn |
  51. Schubert, Ingo |
  52. O'Sullivan, Donal |
  53. Schulman, Alan |
  54. Andersen, Stig U. |
1000 Erscheinungsjahr 2023
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2023-03-08
1000 Erschienen in
1000 Quellenangabe
  • 615(7953):652-659
1000 FRL-Sammlung
1000 Lizenz
1000 Verlagsversion
  • https://dx.doi.org/10.1038/s41586-023-05791-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033403/ |
1000 Ergänzendes Material
  • https://www.nature.com/articles/s41586-023-05791-5#Sec33 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Increasing the proportion of locally produced plant protein in currently meat-rich diets could substantially reduce greenhouse gas emissions and loss of biodiversity(1). However, plant protein production is hampered by the lack of a cool-season legume equivalent to soybean in agronomic value(2). Faba bean (Vicia faba L.) has a high yield potential and is well suited for cultivation in temperate regions, but genomic resources are scarce. Here, we report a high-quality chromosome-scale assembly of the faba bean genome and show that it has expanded to a massive 13 Gb in size through an imbalance between the rates of amplification and elimination of retrotransposons and satellite repeats. Genes and recombination events are evenly dispersed across chromosomes and the gene space is remarkably compact considering the genome size, although with substantial copy number variation driven by tandem duplication. Demonstrating practical application of the genome sequence, we develop a targeted genotyping assay and use high-resolution genome-wide association analysis to dissect the genetic basis of seed size and hilum colour. The resources presented constitute a genomics-based breeding platform for faba bean, enabling breeders and geneticists to accelerate the improvement of sustainable protein production across the Mediterranean, subtropical and northern temperate agroecological zones.
1000 Sacherschließung
lokal metabolism
lokal Genome-Wide Association Study
lokal Plant Proteins
lokal genetics
lokal Plant Breeding
lokal Vicia faba
lokal DNA Copy Number Variations
lokal Diploidy
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-2951-0541|https://orcid.org/0000-0002-9711-4826|https://frl.publisso.de/adhoc/uri/S3JlcGxhaywgSm9uYXRoYW4=|https://orcid.org/0000-0002-8502-9210|https://frl.publisso.de/adhoc/uri/QW5ncmEsIERlZXB0aSA=|https://orcid.org/0000-0001-7070-6015|https://orcid.org/0000-0002-7447-6226|https://orcid.org/0000-0001-8757-9905|https://orcid.org/0000-0002-5858-8105|https://orcid.org/0000-0003-3972-7058|https://orcid.org/0000-0002-3418-3840|https://orcid.org/0000-0001-7787-1849|https://orcid.org/0000-0002-6757-0943|https://frl.publisso.de/adhoc/uri/SGFsbGFiLCBBc2lzIA==|https://orcid.org/0000-0002-8229-8693|https://frl.publisso.de/adhoc/uri/S2VlYmxlLUdhZ27DqHJlLCBHYWJyaWVsIA==|https://frl.publisso.de/adhoc/uri/S29ibMOtxb5rb3bDoSwgQW5kcmVh|https://orcid.org/0000-0001-9024-7717|https://orcid.org/0000-0002-4653-1195|https://orcid.org/0000-0003-0558-1425|https://orcid.org/0000-0001-6711-6639|https://orcid.org/0000-0002-6643-8019|https://orcid.org/0000-0003-3215-9481|https://orcid.org/0000-0002-5068-9681|https://frl.publisso.de/adhoc/uri/T3JhYmksIEppaGFk|https://orcid.org/0000-0003-3125-3695|https://frl.publisso.de/adhoc/uri/Um9iZXJ0c29uLVNoZXJzYnktSGFydmllLCBUb20=|https://frl.publisso.de/adhoc/uri/Um9ibGVkaWxsbywgTGF1cmEgw4F2aWxh|https://frl.publisso.de/adhoc/uri/U2NoaWVtYW5uLCBBbmRyZWEg|https://frl.publisso.de/adhoc/uri/VGFuc2thbmVuLCBKYWFra28=|https://frl.publisso.de/adhoc/uri/VMO2csO2bmVuLCBQZXRyaSA=|https://orcid.org/0000-0002-9281-0443|https://orcid.org/0000-0002-0482-2592|https://orcid.org/0000-0001-7338-0946|https://orcid.org/0000-0002-1867-5730|https://frl.publisso.de/adhoc/uri/Q291cnR5LCBQaWVycmUtRW1tYW51ZWwg|https://orcid.org/0000-0002-6263-0492|https://orcid.org/0000-0002-7807-2966|https://orcid.org/0000-0001-9804-1529|https://orcid.org/0000-0002-5202-8764|https://orcid.org/0000-0003-0829-1570|https://orcid.org/0000-0001-6373-6013|https://orcid.org/0000-0002-6117-8510|https://orcid.org/0000-0001-5577-7616|https://orcid.org/0000-0003-3011-8731|https://orcid.org/0000-0002-8097-5750|https://frl.publisso.de/adhoc/uri/U3RvdWdhYXJkLCBKZW5z|https://frl.publisso.de/adhoc/uri/VGF5ZWgsIE5hZGlt|https://orcid.org/0000-0002-2907-4287|https://orcid.org/0000-0003-0921-8041|https://orcid.org/0000-0002-6300-2068|https://orcid.org/0000-0003-4889-056X|https://orcid.org/0000-0002-4126-6177|https://orcid.org/0000-0002-1096-1468
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  1. The giant diploid faba genome unlocks variation in a global protein crop
    The giant diploid faba genome unlocks variation in a global protein crop
1000 Objektart article
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1000 @id frl:6441223.rdf
1000 Erstellt am 2023-03-31T12:27:17.010+0200
1000 Erstellt von 325
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1000 Bearbeitet von 317
1000 Zuletzt bearbeitet Wed Apr 19 18:46:46 CEST 2023
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