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1000 Titel
  • Genetic Variant of CXCR1 (rs2234671) Associates with Clinical Outcome in Perihilar Cholangiocarcinoma
1000 Autor/in
  1. Lurje, Isabella |
  2. Czigany, Zoltan |
  3. Bednarsch, Jan |
  4. Gaisa, Nadine |
  5. Dahl, Edgar |
  6. Knüchel, Ruth |
  7. Miller, Hannah |
  8. Ulmer, Tom Florian |
  9. Strnad, Pavel |
  10. Trautwein, Christian |
  11. Tacke, Frank |
  12. Neumann, Ulf Peter |
  13. Lurje, Georg |
1000 Erscheinungsjahr 2022
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2022-01-25
1000 Erschienen in
1000 Quellenangabe
  • 11(2):162-173
1000 Copyrightjahr
  • 2022
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1159/000521613 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109077/ |
1000 Publikationsstatus
1000 Abstract/Summary
  • Background!#!Perihilar cholangiocarcinoma (pCCA) is a rare primary liver malignancy. Even in patients amenable to surgery, outcomes are often dismal. Here, we aimed to identify prognostic markers for patient outcomes by analyzing functionally relevant single-nucleotide polymorphisms (SNPs) in genes with a role in tumor inflammation and angiogenesis. We analyzed 11 polymorphisms in the inflammation-angiogenesis axis (!##!Methods!#!Samples were obtained from 111 patients with pCCA undergoing liver resection in curative intent. DNA was extracted and analyzed using polymerase chain reaction-restriction fragment length polymorphism protocols and correlated with patients' outcomes.!##!Results!#!Out of the assessed variants, only the !##!Conclusion!#!Genetic variant of
1000 Sacherschließung
lokal CXCR1
lokal Perihilar cholangiocarcinoma
lokal Single-nucleotide polymorphism
lokal IL-8
lokal Research Article
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-4006-7707|https://frl.publisso.de/adhoc/uri/Q3ppZ2FueSwgWm9sdGFu|https://frl.publisso.de/adhoc/uri/QmVkbmFyc2NoLCBKYW4=|https://orcid.org/0000-0002-4762-3964|https://orcid.org/0000-0002-8439-7994|https://frl.publisso.de/adhoc/uri/S27DvGNoZWwsIFJ1dGg=|https://frl.publisso.de/adhoc/uri/TWlsbGVyLCBIYW5uYWg=|https://frl.publisso.de/adhoc/uri/VWxtZXIsIFRvbSBGbG9yaWFu|https://orcid.org/0000-0002-7122-6379|https://frl.publisso.de/adhoc/uri/VHJhdXR3ZWluLCBDaHJpc3RpYW4=|https://orcid.org/0000-0001-6206-0226|https://frl.publisso.de/adhoc/uri/TmV1bWFubiwgVWxmIFBldGVy|https://orcid.org/0000-0001-9674-0756
1000 Hinweis
  • DeepGreen-ID: 07116c22c41d42e599bf3480eb72c3df ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 @id frl:6441452.rdf
1000 Erstellt am 2023-04-25T14:55:13.948+0200
1000 Erstellt von 322
1000 beschreibt frl:6441452
1000 Zuletzt bearbeitet Sat Oct 14 03:05:24 CEST 2023
1000 Objekt bearb. Sat Oct 14 03:05:24 CEST 2023
1000 Vgl. frl:6441452
1000 Oai Id
  1. oai:frl.publisso.de:frl:6441452 |
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